Purified anti-human CD19 Antibody

Pricing & Availability
Clone
4G7 (See other available formats)
Workshop
HCDM listed
Other Names
B4, CVID3
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
4G7_Pure_CD19_Antibody_011118
Human peripheral blood lymphocytes were stained with purified CD19 (clone 4G7) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram) followed by anti-mouse IgG-FITC.
  • 4G7_Pure_CD19_Antibody_011118
    Human peripheral blood lymphocytes were stained with purified CD19 (clone 4G7) (filled histogram) or purified mouse IgG1, κ isotype control (open histogram) followed by anti-mouse IgG-FITC.
Cat # Size Price Quantity Avail. Save
392502 100 µg 152€
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Description

CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Chronic Lymphocytic Leukemia (CLL) cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Cabezudo E, et al. 1999. Haematologica. 84:413-8
  2. Van Zelm MC et al. 2010. J Clin Invest. 120:1265-74
RRID
AB_2721738 (BioLegend Cat. No. 392502)

Antigen Details

Structure
Ig superfamily, type I transmembrane glycoprotein, 95 kD
Distribution

Normal and malignant B lymphocytes

Function
B cell activation and differentiation
Ligand/Receptor
Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
Cell Type
Lymphocytes, B cells
Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References
  1. Tedder T, et al. 1994. Immunol. Today 15:437.
  2. Bradbury L, et al. 1993. J. Immunol. 151:2915.
Gene ID
930 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

Related FAQs

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Go To Top Version: 0    Revision Date: 01/12/2018

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