PE/Cyanine7 anti-mouse lymphotoxin beta receptor (LTβR) Antibody

Pricing & Availability
Clone
5G11 (See other available formats)
Regulatory Status
RUO
Other Names
LTbR, TNFRIII, TNF receptor-related protein (TNFRrp)
Isotype
Rat IgG2a, κ
Ave. Rating
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Product Citations
publications
5G11_PECy7_LTbetaR_Antibody_032718
C57BL/6 bone marrow cells were stained with Alexa Fluor® 488 Ly-6G/Ly-6C and PE/Cyanine7 anti-mouse lymphotoxin beta receptor (left) or PE/Cyanine7 rat IgG2a, ? isotype control (right).
  • 5G11_PECy7_LTbetaR_Antibody_032718
    C57BL/6 bone marrow cells were stained with Alexa Fluor® 488 Ly-6G/Ly-6C and PE/Cyanine7 anti-mouse lymphotoxin beta receptor (left) or PE/Cyanine7 rat IgG2a, ? isotype control (right).
Compare all formats See PE/Cyanine7 spectral data
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134409 25 µg 240€
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134410 100 µg 556€
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Description

LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
E.coli expressed extracellular domain of mouse lymphotoxin beta receptor
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Additional Product Notes

BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.

RRID
AB_2728152 (BioLegend Cat. No. 134409)
AB_2728153 (BioLegend Cat. No. 134410)

Antigen Details

Distribution

Expressed on stromal cells, monocytes, and certain embryonic epithelial layers.

Function
LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
Ligand/Receptor
LTα1β2 and LIGHT
Cell Type
Embryonic Stem Cells, Epithelial cells, Monocytes
Biology Area
Immunology, Stem Cells
Molecular Family
Adhesion Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Force WR, et al. 1995. J. Immunol. 155:5280
2. Tamada K, et al. 2000. J. Immunol. 164:4105
3. Browing JL, et al. 1997. J. Immunol. 159:3288
4. Futterer A, et al. 1998. Immunity 9:59
5. Nakamura T, et al. 1995. Genomics 30:312
6. Crowe P, et al. 1996. Science 264:707
7. Dejardin E, et al. Immunity 2002. 17(4):525

Gene ID
17000 View all products for this Gene ID
UniProt
View information about LT-betaR on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 03/28/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse lymphotoxin beta receptor (LTβR)

  • PE anti-mouse lymphotoxin beta receptor (LTβR)

  • PE/Cyanine7 anti-mouse lymphotoxin beta receptor (LTβR)

  • APC anti-mouse lymphotoxin beta receptor (LTβR)

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