- 3C10C5 (See other available formats)
- Regulatory Status
- Other Names
- Toll like receptor 10
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD290, also known as TLR10, is a 91-100 kD glycosylated protein belonging to the toll-like receptor family. It is expressed on B cell, Treg cells, and plasmacytoid dendritic cells but absent on T cells, particularly non-Treg and granulocytes. It can interact with MyD88 and plays an important role in innate immunity and pattern recognition.Product Details
- Verified Reactivity
- Human, Baboon
- Antibody Type
- Host Species
- Purified extracellular domain of human TLR10 (amino acids 20-474) (NP_001017388 )
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
View more applications data for this product in our Scientific Poster Library.
(PubMed link indicates BioLegend citation)
- Guan Y, et al. 2010. J. Immunol. 184:5094.
AB_11219598 (BioLegend Cat. No. 354603)
AB_11219791 (BioLegend Cat. No. 354604)
- Member of the toll-like receptor family, type I membrane protein, 91-100 kD
B cells, Treg cells, plasmacytoid DCs
- Interacts with MyD88 and TRAF6, which results in NF-kB activation and cytokine secretion
- MyD88 and TRAF6
- Cell Type
- B cells, Tregs, Dendritic cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Toll Like Receptors
- Antigen References
1. Chuang T, et al. 2001. Biochim. Biophys. Acta. 1518:157.
2. Hornung V, et al. 2002. J. Immunol. 168:4531.
3. Bourke E, et al. 2003. Blood 102:956.
- Gene ID
- 81793 View all products for this Gene ID
- View information about CD290 on UniProt.org
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
|PE anti-human CD290 (TLR10)||3C10C5||FC|
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