PE anti-human CD286 (TLR6) Antibody

Pricing & Availability
TLR6.127 (See other available formats)
Regulatory Status
Other Names
TLR6, CD286
Mouse IgG1, κ
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Product Citations
Human peripheral blood monocytes stained with TLR6.127 PE
  • TLR6dot127_PE_121508.jpg
    Human peripheral blood monocytes stained with TLR6.127 PE
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334707 25 tests 248€
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334708 100 tests 520€
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Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been identified. Toll-like receptor 6 (TLR6), known as CD286, is one of the important receptors. TLR6 is colocalized with TLR2 on the cell surface of monocytes/macrophages, dendritic cells, granulocytes. The TLR2/TLR6 complex plays a role in the innate immune response to diacylated lipoprotein and peptidoglycan antigens.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Human TLR6 transfected Ba/F3 cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: blocks cytokine production induced by MALP-2 and peptidoglycan(1)

Application References

(PubMed link indicates BioLegend citation)
  1. Nakao Y, et al. 2005. J. Immunol. 174:1566
Product Citations
  1. Whitmore L, et al. 2016. J Immunol. 196: 1376 - 1386. PubMed
AB_2205398 (BioLegend Cat. No. 334707)
AB_2205397 (BioLegend Cat. No. 334708)

Antigen Details

Type I transmembrane protein characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain, colocalized with TLR2 at the cell surface
Monocytes/macrophages, dendritic cells, granulocytes
Activates innate host defense against diverse set of pathogens
Diacylated lipoprotein, peptidoglycan
Cell Type
Monocytes, Macrophages, Dendritic cells, Granulocytes
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules, Toll Like Receptors
Antigen References

1. Takeuchi O, et al. 2001. Int. Immunol. 13:933
2. Shimizu T, et al. 2005. J. Immunol. 175:4641
3. Into T, et al. 2004. Cell Microbiol. 6:187

Gene ID
10333 View all products for this Gene ID
View information about CD286 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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