APC anti-human CD19 Antibody

Pricing & Availability
Clone
4G7 (See other available formats)
Workshop
HCDM listed
Other Names
B4, CVID3
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
4G7_APC_CD19_Antibody_031918
Human peripheral blood lymphocytes were stained with CD19 (clone 4G7) (filled histogram) APC or mouse IgG1, κ isotype control (open histogram) APC.
  • 4G7_APC_CD19_Antibody_031918
    Human peripheral blood lymphocytes were stained with CD19 (clone 4G7) (filled histogram) APC or mouse IgG1, κ isotype control (open histogram) APC.
See APC spectral data
Cat # Size Price Quantity Avail. Save
392503 25 tests 144€
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392504 100 tests 296€
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Description

CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human Chronic Lymphocytic Leukemia (CLL) cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Cabezudo E, et al. 1999. Haematologica. 84:413-8
  2. Van Zelm MC et al. 2010. J Clin Invest. 120:1265-74
RRID
AB_2728415 (BioLegend Cat. No. 392503)
AB_2728416 (BioLegend Cat. No. 392504)

Antigen Details

Structure
Ig superfamily, type I transmembrane glycoprotein, 95 kD
Distribution

Normal and malignant B lymphocytes

Function
B cell activation and differentiation
Ligand/Receptor
Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
Cell Type
Lymphocytes, B cells
Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References
  1. Tedder T, et al. 1994. Immunol. Today 15:437.
  2. Bradbury L, et al. 1993. J. Immunol. 151:2915.
Gene ID
930 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 0    Revision Date: 03/19/2018

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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