Chemokine Signaling

Chemokines are a subset of cytokines that specifically induce chemotaxis of cells with the appropriate G-protein coupled receptors. Upon chemokine binding to the receptor, G-proteins on the cytoplasmic surface of the plasma membrane induce a number of pathways. These varied pathways lead to the promotion of cell survival, proliferation, and cytoskeletal changes that induce cell migration.

 

Click on the poster below to view the interactive version.

 

Chemokine Signaling

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