BioLegend Growth Factors
Growth factors act as signaling molecules that regulate a number of critical cellular processes including proliferation, differentiation, migration, and development. We offer a wide range of antibodies and recombinant proteins to study growth factors in a variety of applications including bioassays, ELISAs, multiplexing, Western blotting, flow cytometry and microscopy. Visit the pages below to learn more about the different growth factor families!
BMP   EGF   FGF   Hedgehog   IGF   Neurotrophic
PDGF   Stem Cell   TGF   TNF   VEGF   Other
Growth Factors Overview
Growth factors include both cytokines and hormones which act as signaling molecules regulating a number of cellular processes including proliferation, differentiation, and apoptosis. Because these pathways are critical for cell growth and survival, these pathways are often dysregulated in disease states such as cancer. Most commonly, growth factors bind to receptor tyrosine kinases on the cell surface inducing dimerization and autophosphorylation of the receptors. Phosphorylation of the receptor initiates signaling through downstream pathways altering gene expression and cell cycle regulation ultimately modulating a number of critical cell processes including proliferation, differentiation, migration, angiogenesis and inhibition of apoptosis.
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