Spark YG™ 581 anti-human CD56 (NCAM) Recombinant Antibody

Pricing & Availability
Clone
QA17A16 (See other available formats)
Regulatory Status
RUO
Other Names
Leu-19, NKH1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA17A16_SPKYG581_CD56_RECOM_Antibody_121720_updated_2.png
Human peripheral blood lymphocytes were stained with anti-human CD3 Brilliant Violet 421™ and anti-human CD56 recombinant (clone QA17A16) Spark YG™ 581 (left), and only stained with anti-human CD3 Brilliant Violet 421™ (right).
  • QA17A16_SPKYG581_CD56_RECOM_Antibody_121720_updated_2.png
    Human peripheral blood lymphocytes were stained with anti-human CD3 Brilliant Violet 421™ and anti-human CD56 recombinant (clone QA17A16) Spark YG™ 581 (left), and only stained with anti-human CD3 Brilliant Violet 421™ (right).
Compare all formats See Spark YG™ 581 spectral data
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392429 25 tests 100€
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392430 100 tests 249€
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Description

CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Spark YG™ 581 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Spark YG™ 581 has a maximum excitation of 562 nm and a maximum emission of 581 nm.

Excitation Laser
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2890829 (BioLegend Cat. No. 392429)
AB_2890829 (BioLegend Cat. No. 392430)

Antigen Details

Structure
Ig superfamily, single transmembrane or GPI-anchored glycoprotein
Distribution

NK cells, NK-Tcells, brain and neuromuscular junctions, certain large granular lymphocyte (LGL) leukemias, small-cell lung carinomas, neuronal derived tumors, myelomas, and myeloid leukemias

Function
Adhesion
Ligand/Receptor
Heparin sulfate
Cell Type
Leukemia, Neurons, NK cells, NKT cells
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Lanier L, et al. 1991. J. Immunol. 146:4421.
2. Hemperly J, et al. 1990. J. Mol. Neurosci. 2:71.
3. Cremer H, et al. 1994. Nature 367:455.

Gene ID
4684 View all products for this Gene ID
UniProt
View information about CD56 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All CD56 Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
APC anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
Alexa Fluor® 700 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
APC/Fire™ 750 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE/Dazzle™ 594 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
FITC anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE/Cyanine7 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
Pacific Blue™ anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
TotalSeq™-A0084 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 PG
PerCP/Cyanine5.5 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
TotalSeq™-B0084 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 PG
TotalSeq™-C0084 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 PG
PE/Fire™ 700 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
Spark YG™ 581 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE/Fire™ 640 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE anti-human CD56 QA17A16 FC
APC/Fire™ 750 anti-human CD56 QA17A16 FC
APC anti-human CD56 QA17A16 FC
FITC anti-human CD56 QA17A16 FC
PerCP/Cyanine5.5 anti-human CD56 QA17A16 FC
PE/Cyanine7 anti-human CD56 QA17A16 FC
Pacific Blue™ anti-human CD56 QA17A16 FC
PE/Dazzle™ 594 anti-human CD56 QA17A16 FC
Spark Red™ 718 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
PE/Fire™ 810 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
Spark PLUS UV™ 395 anti-human CD56 (NCAM) Recombinant Antibody QA17A16 FC
Go To Top Version: 1    Revision Date: 12/17/2020

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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