- W20001B (See other available formats)
- Regulatory Status
- Other Names
- Heat stable antigen (HSA), nectadrin, Ly-52
- Mouse IgG2b, κ
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- Product Citations
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CD24 is a 35-45 kD glycosylphosphatidylinositol (GPI)-linked protein also known as heat stable antigen (HSA), BA-1, Ly-52, and nectadrin. It is expressed on the surface of B cells (but not plasma cells), granulocytes, follicular dendritic cells, and epithelial cells. CD24 may play a role in the regulation of B-cell proliferation and maturation. CD24 crosslinking induces a Ca2+ flux in mature B cells. CD24 has been shown to interact with CD62P (P-selectin).Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Recombinant human CD24 protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone W20001B can partially block binding of clone ML5 on target cells and is partially blocked by ML5.
AB_2922617 (BioLegend Cat. No. 382602)
- 35-45 kD glycosylphosphatidylinos GPI-linked protein
B lymphocytes, granulocytes, differentiating neurons, and epithelial cells
- Regulates B-cell proliferation and activation
- P-Selectin and Siglec-10
- Cell Type
- B cells, Epithelial cells, Granulocytes, Lymphocytes, Neural Stem Cells, T cells, Thymocytes
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immuno-Oncology, Immunology, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
- Schlossman S, et al. 1995. Leukocyte Typing V. Oxford University Press. New York.
- Fang X, et al. 2010. Cellular and Molecular Immunology. 7:100-3.
- Gene ID
- 100133941 View all products for this Gene ID
- View information about CD24 on UniProt.org
|Purified anti-human CD24||W20001B||FC|
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