- Poly28635 (See other available formats)
- Regulatory Status
- Other Names
- ADH1, Alcohol Dehydrogenase 1C (Class I), Gamma Polypeptide, Alcohol Dehydrogenase Subunit Gamma, Aldehyde Reductase, EC 1.1.1
- Rabbit Polyclonal IgG
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- Product Citations
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ADH1 is the γ subunit of class I alcohol dehydrogenase. The alcohol dedydrogenase family is involved in metabolization of a variety of substrates, including ethanol and lipid peroxidation products. ADH1 is related to the signaling pathway of cytochrome P450 metabolism. It is also associated with several diseases including late-onset Parkinson Disease.Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Host Species
- Recombinant Alcohol Dehydrogenase 1 (ADH1) expressed in E.coli.
- 0.01 M PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.
- 0.5 mg/mL
- Storage & Handling
- Store at 4°C for up to 3 months. For longer term storage, aliquot into small volumes and store at -20°C.
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 µg/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2820148 (BioLegend Cat. No. 863501)
- ADH1 is a 375 amino acid protein with an apparent molecular mass of ~39 kD.
Tissue Distribution: Liver, kidney, pancreas, and gallbladder
Cellular Distribution: Cytosol and nucleus
- ADH1 is involved in ethanol and hydroxysteroids metabolism.
- Ethanol, retinol, hydroxysteroids
- Cell Type
- Mesenchymal cells
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience
- Molecular Family
- Aldehyde Dehydrogenases
- Antigen References
- Lieber CS. 2004. Alcohol. 34(1):9-19.
- Zuo L, et al. 2013. Hum Genet. 132(7):735-43.
- Dumont S, et al. 2018. PLoS One. 13(9):e0204530.
- Gene ID
- 126 View all products for this Gene ID 11522 View all products for this Gene ID 24172 View all products for this Gene ID
- View information about ADH1 on UniProt.org
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