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FITC anti-human TCR Vγ9 Antibody

Pricing & Availability
Clone
B3 (See other available formats)
Regulatory Status
RUO
Other Names
T cell receptor Vγ9
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
B3_FITC_021309.jpg
Human peripheral blood lymphocytes stained with CD3 APC and B3 FITC
  • B3_FITC_021309.jpg
    Human peripheral blood lymphocytes stained with CD3 APC and B3 FITC
Compare all formats See FITC spectral data
Cat # Size Price Quantity Check Availability Save
331305 25 tests 76€
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331306 100 tests 169€
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Description

The Vγ9 TCR is a variant of the TCR γ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is a heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
Chimpanzee, Cynomolgus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application References
  1. Van Rhijn I, et al. 2003. Intl. Immunol. 15:373.
  2. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
Product Citations
  1. Franchini DM et al. 2019. Cell reports. 26(1):94-107 . PubMed
RRID
AB_1236435 (BioLegend Cat. No. 331305)
AB_1236403 (BioLegend Cat. No. 331306)

Antigen Details

Structure
Ig superfamily member, TCR γ/δ with CD3 forms the CD3/TCR complex
Distribution

Expressed on majority of peripheral γ/δ T cells

Function
Antigen recognition, T cell activation
Ligand/Receptor
Peptide bound to MHC
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
TCRs
Antigen References
  1. Scotet E, et al. 2005. Immunity 22:71
  2. Rincon-Orozco B, et al. 2005. J. Immunol. 175:2144
Gene ID
6965 View all products for this Gene ID
UniProt
View information about TCR Vgamma9 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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