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Biotin anti-human CD155 (PVR) Antibody

Pricing & Availability
Clone
SKII.4 (See other available formats)
Regulatory Status
RUO
Other Names
Poliovirus receptor (PVR), nectin-like 5
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
SKII4_Biotin_CD155_Antibody_110917
U937 cells were stained with biotinylated CD155 (clone SKII.4) (filled histogram) or biotinylated mouse IgG1, κ isotype control (open histogram), followed by SAV-PE.
  • SKII4_Biotin_CD155_Antibody_110917
    U937 cells were stained with biotinylated CD155 (clone SKII.4) (filled histogram) or biotinylated mouse IgG1, κ isotype control (open histogram), followed by SAV-PE.
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337620 100 µg 212€
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Description

CD155, known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. It is a nectin-like molecule belonging to Ig superfamily. CD155 is primarily found on endothelial cells, monocytes, epithelia and central nervous system. CD155 is an adhesion molecule involved in cell-cell and cell-matrix adhesion through interaction with CD226, CD96 (Tactile), nectin-1, -2, and -3 (CD111, CD112, CD113), and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
SK-N-S1 human neuroblastoma cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications include: block binding of PVR ligands CD226 and CD96 to PVR, immunoprecipitation, and western blot.

Application References
  1. Fuchs A, et al. 2004. J. Immunol. 172:3994
RRID
AB_2721493 (BioLegend Cat. No. 337620)

Antigen Details

Structure
Type I glycoprotein, Ig superfamily
Distribution

Monocytes, endothelial cells, epithelia, central nervous system

Function
Cell-cell and cell-matrix adhesion
Ligand/Receptor
CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus
Cell Type
Endothelial cells, Epithelial cells, Monocytes, Tregs
Biology Area
Immunology, Innate Immunity
Molecular Family
Adhesion Molecules, CD Molecules, Immune Checkpoint Receptors
Antigen References

1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication
2. Bottino PD, et al. 2005. Mol. Immunol. 42:463
3. Tahara-Hanaoka S, et al. 2004. Intl. Immunol. 16:533

Gene ID
5817 View all products for this Gene ID
UniProt
View information about CD155 on UniProt.org

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 0    Revision Date: 11/09/2017

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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