APC anti-human CD96 (TACTILE) Antibody

Pricing & Availability
Clone
NK92.39 (See other available formats)
Regulatory Status
RUO
Other Names
Tactile (T cell-activated increased late expression)
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
NK92.39_APC_CD96_Antibody_FC_1_080715
Human peripheral blood lymphocytes were co-stained with CD19 FITC and CD96 (clone NK92.39) APC (top) or mouse IgG1, κ APC isotype control (bottom).
  • NK92.39_APC_CD96_Antibody_FC_1_080715
    Human peripheral blood lymphocytes were co-stained with CD19 FITC and CD96 (clone NK92.39) APC (top) or mouse IgG1, κ APC isotype control (bottom).
  • NK92.39_APC_CD96_Antibody_FC_2_080715
Compare all formats See APC spectral data
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338409 25 tests 120€
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338410 100 tests 271€
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Description

CD96, known as TACTILE (T cell-activated increased late expression), is a 160 kD type I transmembrane glycoprotein and is a member of the Ig superfamily molecules. It is expressed on NK cells, T cells (up-regulated upon activation), and some acute myeloid leukemia (AML) cells, but not on normal B and myeloid cells. A soluble form of CD96 has been found in serum. CD96 is involved in T- and NK-cell adhesion through interaction with its ligand, CD155 (polio virus receptor).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications include: block interaction of CD96 with PVR and functional assay

Application References
  1. Fuchs A, et al. 2004. J. Immunol. 172:3994
  2. Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
Product Citations
  1. Alhaj Hussen K, et al. 2017. Immunity. 47:680. PubMed
  2. Huang RS, et al. 2021. Curr Protoc. 1:e246. PubMed
RRID
AB_2566141 (BioLegend Cat. No. 338409)
AB_2566142 (BioLegend Cat. No. 338410)

Antigen Details

Structure
160 kD, type I transmembrane protein, Ig superfamily
Distribution

NK cells, T cells (upregulated upon activation)

Ligand/Receptor
CD155 (PVR)
Cell Type
NK cells, T cells
Biology Area
Immunology, Innate Immunity, Inhibitory Molecules
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol.

Gene ID
10225 View all products for this Gene ID
UniProt
View information about CD96 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 08/17/2015

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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