Alexa Fluor® 647 anti-human CD336 (NKp44) Antibody

Pricing & Availability
P44-8 (See other available formats)
Regulatory Status
Other Names
NKp44, NCR2, Activating NK receptor NKp44, natural cytotoxicity triggering receptor 2. lymphocyte antigen 95 homolog
Mouse IgG1, κ
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Product Citations
Human PBMCs were stimulated with rhIL-2 for 9 days, then stained with CD56 PE and P44-8 Alexa Fluor® 647
  • P44-8_Alx647_071007
    Human PBMCs were stimulated with rhIL-2 for 9 days, then stained with CD56 PE and P44-8 Alexa Fluor® 647
Compare all formats See Alexa Fluor® 647 spectral data
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325112 100 tests 238€
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CD336 is also known as activating NK receptor NKp44 (NKp44), natural cytotoxicity triggering receptor 2, and lymphocyte antigen 95 homolog. It is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp44 has an apparent molecular weight of 44 kD and three isoforms are produced by alternative splicing. NKp44 is expressed on IL-2 activated NK cells and a subset of γ/δ T cells. NKp44 enhances NK cell mediated cytolysis of virus infected cells and tumor cells. NKp44 has been shown to associate with the intracellular adaptor DAP12.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Host Species
recombinant human NKp44
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.

Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application Notes

The p44-8 antibody against human NKp44 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp44 in a redirected lysis assay, and blocking of NKp44 function in solution. Additional reported applications (for the relevant formats) include: stimulation of human NK cells via NKp44 in a redirected lysis assay, and blocking of NKp44 function in solution1,2. The LEAF™ purified antibody (Endotoxin < 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 325104).

Application References
  1. Sommaggio R, et al. 2012. J. Immunol. 188:2075. (Block)
  2. Hoechst B, et al. 2009. Hepatology. 50:799. (Block) PubMed
  3. Correia DV, et al. 2011. Blood. 118:992. (FC) PubMed
Product Citations
  1. Ponath V, et al. 2021. Int J Mol Sci. 22:. PubMed
  2. Damele L, et al. 2021. Cancers (Basel). 13:. PubMed
  3. Hood SP, et al. 2020. Elife. 9:00. PubMed
  4. Bal S, et al. 2016. Nat Immunol. 10.1038/ni.3444. PubMed
AB_2149431 (BioLegend Cat. No. 325112)

Antigen Details

Type I transmembrane protein, member of the natural cytotoxicity receptor family, contains one immunoglobulin-like domain. Approximately 44 kD. Three isoforms produced by alternative splicing.

IL-2 activated NK cells and cell lines, some γ/δ T cells activated in vitro

NK cell triggering of cytolysis toward tumor targets and other target cells deficient in MHC class I molecules
Cell Type
NK cells, T cells
Biology Area
Molecular Family
CD Molecules
Antigen References

1. Cantoni C, et al. 1999. J. Exp. Med. 189:787.
2. Allcock RJN, et al. 2003. Eur. J. Immunol. 33:567.
3. Cantoni C, et al. 2003. Structure. 11:725.

Gene ID
9436 View all products for this Gene ID
View information about CD336 on

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Go To Top Version: 3    Revision Date: 06/27/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • APC anti-human CD336 (NKp44)

  • Alexa Fluor® 647 anti-human CD336 (NKp44)

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  • Ultra-LEAF™ Purified anti-human CD336 (NKp44)

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  • TotalSeq™-D0802 anti-human CD336 (NKp44)


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