- 7D4-6 (See other available formats)
- Regulatory Status
- Other Names
- KDR, Vascular Endothelial Receptor 2 (VEGF-R2, VEGFR2, VEGFR)
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
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CD309, also known as VEGF-R2, KDR, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, and VEGF-D splice isoforms. Activation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.Product Details
- Antibody Type
- Host Species
- Human KDR recombinant protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses
- Excitation Laser
Red Laser (633 nm)
- Product Citations
AB_2563488 (BioLegend Cat. No. 359909)
AB_2563489 (BioLegend Cat. No. 359910)
- Type I transmembrane glycoprotein, type III tyrosine kinase receptor, CSF-1/PDGF receptor family
Endothelial cells, embryonic tissues
- VEGF-A, VEGF-C, and VEGF-D splice isoforms
- Cell Type
- Endothelial cells
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication.
2. Ferrara N and Gerber HP. 2002. Acta. Haematol. 106:148.
3. Murohara T, et al. 1998. Circulation. 97:99.
- Gene ID
- 3791 View all products for this Gene ID
- View information about CD309 on UniProt.org
|Purified anti-human CD309 (VEGFR2)||7D4-6||FC, ICC|
|PE anti-human CD309 (VEGFR2)||7D4-6||FC|
|PerCP/Cyanine5.5 anti-human CD309 (VEGFR2)||7D4-6||FC|
|Alexa Fluor® 647 anti-human CD309 (VEGFR2)||7D4-6||FC|
|PE/Cyanine7 anti-human CD309 (VEGFR2)||7D4-6||FC|
|Alexa Fluor® 488 anti-human CD309 (VEGFR2)||7D4-6||FC|
|APC anti-human CD309 (VEGFR2)||7D4-6||FC|
|PE/Dazzle™ 594 anti-human CD309 (VEGFR2)||7D4-6||FC|
|TotalSeq™-A0362 anti-human CD309 (VEGFR2)||7D4-6||PG|
|TotalSeq™-C0362 anti-human CD309 (VEGFR2)||7D4-6||PG|
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-human CD309 (VEGFR2)
PE anti-human CD309 (VEGFR2)
PerCP/Cyanine5.5 anti-human CD309 (VEGFR2)
Alexa Fluor® 647 anti-human CD309 (VEGFR2)
PE/Cyanine7 anti-human CD309 (VEGFR2)
Alexa Fluor® 488 anti-human CD309 (VEGFR2)
APC anti-human CD309 (VEGFR2)
PE/Dazzle™ 594 anti-human CD309 (VEGFR2)
TotalSeq™-A0362 anti-human CD309 (VEGFR2)
TotalSeq™-C0362 anti-human CD309 (VEGFR2)