Purified anti-human IL-7 Antibody

Pricing & Availability
BVD10-40F6 (See other available formats)
Regulatory Status
Other Names
Interleukin-7, Lymphopoietin-1 (LP-1), Pre-B cell growth factor, Thymocyte growth factor
Rat IgG1, κ
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Product Citations
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501302 500 µg 238€
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IL-7 is a potent lymphoid cell growth factor which promotes the proliferation of pre-B cells, thymocytes, T cell progenitors, and mature T cells. IL-7 induces formation of LAK cells and CTLs, and can stimulate tumoricidal activity of monocytes and macrophages. IL-7 can induce upregulation of proinflammatory cytokines in myeloid cells. IL-7 is expressed by stromal cells. The BVD10-40F6 antibody can neutralize the bioactivity of natural or recombinant IL-7.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
E. coli - expressed, recombinant human IL-7
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

ELISA Capture - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-6 µg/ml is recommended. To obtain a linear standard curve, serial dilutions of IL-7 recombinant protein ranging from 500 to 4 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

ELISA or ELISPOT Capture1,2: The purified BVD10-40F6 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the Biotin anti-human IL-7 antibody (Cat. No. 506602) as the detecting antibody. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture.
Neutralization1: The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human IL-7 bioactivity (Cat. No. 501305 & 501306).
Additional reported applications (for the relevant formats) include: Western blotting.

Application References

(PubMed link indicates BioLegend citation)
  1. Abrams J, et al. 1992. Immunol. Rev. 127:5.
  2. Abrams J. 1995. Curr. Prot. Immunol.. John Wiley and Sons New York. Unit 6.20.
Product Citations
  1. Haug V, et al. 2020. Transplantation. e260:104. PubMed
  2. Gilboa T, et al. 2020. Adv Healthc Mater. e2001111:. PubMed
AB_315164 (BioLegend Cat. No. 501302)

Antigen Details

Cytokine; 20-28 kD (Mammalian)
Proliferation of pre-/pro-B cells, thymocytes, T cells; formation of LAK cells, CTLs, stimulation of tumoricidal activity monocytes/macrophages; upregulate proinflammatory cytokines in myeloid cells
Cell Sources
Adherent bone marrow stromal cells, thymic stromal cells, spleen, keratinocytes
Cell Targets
Progenitor B and T cells; CD4-CD8- thymocytes; megakaryocytes
Heterodimer IL-7Rα (CD127); γ-subunit (CD132) in common with IL-2R, IL-4R, IL-13R, IL-15R
Biology Area
Molecular Family
Antigen References

1. Fitzgerald K, et al. Eds. 2001. The Cytokine FactsBook. Academic Press San Diego.
2. Park L, et al. 1992. Adv. Exp. Med. Biol. 323 125.
3. Melchers F, et al. 1992. Adv. Exp. Med. Biol. 323 111.

Downregulated by TGF-β
Gene ID
3574 View all products for this Gene ID
View information about IL-7 on UniProt.org

Related FAQs

There are no FAQs for this product.

Other Formats

View All IL-7 Reagents Request Custom Conjugation
Description Clone Applications
Purified anti-human IL-7 BVD10-40F6 ELISA Capture
Ultra-LEAF™ Purified anti-human IL-7 BVD10-40F6 ELISA Capture,ELISPOT Capture,Neut,WB
Go To Top Version: 2    Revision Date: 06/28/2013

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • Purified anti-human IL-7

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