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Purified anti-human CD19 Recombinant Antibody

Pricing & Availability
Clone
QA18A75 (See other available formats)
Regulatory Status
RUO
Other Names
B4
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA18A75_PURE_CD19_RECOM_Antibody_032422
Human peripheral blood lymphocytes were stained with purified anti-human CD19 (clone QA18A75) (left) or purified mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG. Cells were co-stained with anti-human CD3 APC.
  • QA18A75_PURE_CD19_RECOM_Antibody_032422
    Human peripheral blood lymphocytes were stained with purified anti-human CD19 (clone QA18A75) (left) or purified mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG. Cells were co-stained with anti-human CD3 APC.
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309502 100 µg 90€
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Description
CD19, also known as B4, is a 95 kD type I transmembrane glycoprotein. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.
Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

From in-house testing, clone QA18A75 blocks binding of clone HIB19 on target cells.

RRID
AB_2910383 (BioLegend Cat. No. 309502)

Antigen Details

Structure
Ig superfamily, type I transmembrane glycoprotein, 95 kD
Distribution

B lineage (except plasma cells), follicular dendritic cells

Function
B cell activation and differentiation
Interaction
CD21 (CR2), CD81 (TAPA-1), BCR
Cell Type
B cells, Leukemia, Lymphocytes
Biology Area
Adaptive Immunity, Immuno-Oncology, Signal Transduction
Molecular Family
CD Molecules
Antigen References
  1. Tedder TF, et al. 1994. Immunol. Today 15:437-42.
  2. Bradbury LE, et al. 1993. J Immunol. 151:2915-27.
Gene ID
930 View all products for this Gene ID
UniProt
View information about CD19 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 03/24/2022

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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