- A17136C (See other available formats)
- Regulatory Status
- Other Names
- B4, CVID3
- Mouse IgG2b, κ
- Ave. Rating
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- Product Citations
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CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Recombinant human CD19
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
AB_2894554 (BioLegend Cat. No. 396302)
- Ig superfamily, type I transmembrane glycoprotein, 95 kD
Normal and malignant B lymphocytes
- B cell activation and differentiation
- Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells and interacts with VAV and LYN. It also interacts with GRAB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378 and with PLCG2 when phosphorylated on Tyr-409.
- Forms complex with CD21 (CR2) and CD81 (TAPA-1), BCR coreceptor
- Cell Type
- B cells, Lymphocytes
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
- Tedder T, et al. 1994. Immunol Today. 15:437.
- Bradbury L, et al. 1993. J Immunol. 151:2915.
- Gene ID
- 930 View all products for this Gene ID
- View information about CD19 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD19 Reagents Request Custom Conjugation
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|Purified anti-human CD19||A17136C||IHC-P|
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