Purified anti-human CD142 Antibody

Pricing & Availability
NY2 (See other available formats)
Regulatory Status
Other Names
Coagulation Factor III, Tissue Factor (TF), Thromboplastin, platelet tissue factor, factor III, factor 3, F3, F-3, TFA
Mouse IgG1, κ
Ave. Rating
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Product Citations
LPS-stimulated human monocytes were stained with purified CD142 (clone NY2) (filled histogram), or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
  • NY2_PURE_CD142_Antibody_FC_121014
    LPS-stimulated human monocytes were stained with purified CD142 (clone NY2) (filled histogram), or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG FITC.
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365202 100 µg 109€
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CD142, also known as Tissue Factor (TF), Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. NULL, et al. 2022. Cell. 185:916. PubMed
AB_2564564 (BioLegend Cat. No. 365202)

Antigen Details

45 kD Type I transmembrane glycoprotein.

Smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells, astrocytes, myocardium, liver stromal cells, pancreas cell, stimulated endothelial cells, stimulated monocytes

Blood coagulation
Coagulation Factor VII
Cell Type
Astrocytes, Endothelial cells, Epithelial cells, Fibroblasts
Biology Area
Angiogenesis, Cell Biology, Immunology
Molecular Family
CD Molecules
Antigen References

1. Carson SD, et al. 1994. Blood 84:526.
2. McComb RD, et al. 1991. Am. J. Pathol. 139:491.
3. Whittle SM, et al. 1995. Thromb. Res. 79:451.

Gene ID
2152 View all products for this Gene ID
View information about CD142 on UniProt.org

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Go To Top Version: 1    Revision Date: 12/16/2014

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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