Purified anti-human β2-microglobulin Antibody

Pricing & Availability
A17082A (See other available formats)
Regulatory Status
Other Names
β2M, β2-M, beta2-microglobulin b2-M, b2M
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes were stained with purified B2M (clone A17082A filled histogram) or mouse IgG1,κ isotype control (open histogram) followed by anti-mouse IgG PE.
  • A17082A_Purified_B2-microglobulin_Antibody_120418
    Human peripheral blood lymphocytes were stained with purified B2M (clone A17082A filled histogram) or mouse IgG1,κ isotype control (open histogram) followed by anti-mouse IgG PE.
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395702 100 µg 287€
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β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant human Beta2-microglobulin
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone A17082A partially cross-blocks anti-human ß2-microglobulin clone 2M2 and does not block anti-human HLA-A,B,C clone W6/32 staining, based on in-house testing.

AB_2783318 (BioLegend Cat. No. 395702)

Antigen Details

12 KD, Ig like structure

Leukocytes, platelets, endothelial cells, epithelial cells and other nucleated cells.

Form MHC class I
MHC class I heavy chain and other MHC I like molecules.
Cell Type
Antigen-presenting cells, Endothelial cells, Epithelial cells, Leukocytes, Platelets
Biology Area
Cancer Biomarkers, Immunology, Innate Immunity
Molecular Family
MHC Antigens
Antigen References
  1. Engelhard VH. 1994. Curr. Opin. Immunol. 6:13.
  2. Williams DB, et al. 1989. J. Immunol. 142:2796.
  3. Danliczyk UG and TL. Delovitch. 1994. J. Immunol. 153:3533.
  4. Williams A, et al. 2002. Tissue Antigens. 59:3.
Gene ID
567 View all products for this Gene ID
View information about beta2-microglobulin on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 12/04/2018

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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