PE anti-mouse CD106 Antibody

Pricing & Availability
429 (MVCAM.A) (See other available formats)
Regulatory Status
Other Names
Rat IgG2a, κ
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Product Citations
C57BL/6 bone marrow cells stained with 429 PE (gated on myeloid cell population)
  • 429_PE_011909.jpg
    C57BL/6 bone marrow cells stained with 429 PE (gated on myeloid cell population)
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105713 50 µg 92€
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105714 200 µg 244€
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CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α41 integrin) and LPAM-1 (α47 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Mouse preadipose cell line PA6
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining2,3,5-7 of acetone-fixed frozen sections, blocking4,5,8 of ligand binding in vitro and in vivo, immunoprecipitation1 , and spacial biology (IBEX)11,12. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 105727 & 105728).

Application References

(PubMed link indicates BioLegend citation)
  1. Kinashi T, et al. 1995. J. Leukoc. Biol. 57:168. (IP)
  2. Koni PA, et al. 2001. J. Exp. Med. 193:741. (IHC)
  3. Ishiyama N, et al. 1998. Pathobiology 66:274. (IHC)
  4. Kinashi T, et al. 1994. Blood Cells 20:25. (Block)
  5. Baron JL, et al. 1994. J. Clin. Invest. 93:1700. (Block IHC)
  6. Buck CA, et al. 1996. Cell Adhes. Commun. 4:69. (IHC)
  7. Hata H, et al. 2004. J. Clin. Invest. 114:582. (IHC)
  8. Meunier MC, et al. 2005. Nature Medicine 11:1222. (Block) PubMed
  9. Monnier J, et al. 2012. J. Immunol. 189:956. PubMed
  10. Motohashi N, et al. 2013. J Cell Sci. 126:2678. PubMed
  11. Radtke AJ, et al. 2020. Proc Natl Acad Sci U S A. 117:33455-65. (SB) PubMed
  12. Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed
Product Citations
  1. Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
  2. Yalamanoglu A, et al. 2021. Front Immunol. 627944:12. PubMed
  3. Silva C, et al. 2019. Cell Physiol Biochem. 52:503. PubMed
  4. Anastasiou M, et al. 2021. JCI Insight. 6:. PubMed
  5. Toda S, et al. 2014. Blood. 123:3963. PubMed
  6. He W et al. 2018. Immunity. 49(6):1175-1190 . PubMed
  7. Reddy A, et al. 2020. Cell. 183:62. PubMed
  8. Moretti FA, et al. 2018. Elife. 7:e35816. PubMed
  9. Garcia-Bonilla L, et al. 2014. J Immunol. 193:2531. PubMed
  10. Philip E Boulais et al. 2018. Immunity. 49(4):627-639 . PubMed
  11. Kwok T, et al. 2022. Front Aging. 3:838943. PubMed
  12. Prontera C, et al. 2007. J Am Coll Cardiol . 49:2182. PubMed
  13. Thomson CA, et al. 2018. J Immunol. 201:215. PubMed
AB_1134166 (BioLegend Cat. No. 105713)
AB_1134164 (BioLegend Cat. No. 105714)

Antigen Details

Ig superfamily, 47 kD

Bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells

VLA-4 (α41 integrin) and LPAM-1 (α47 integrin)
Cell Type
Dendritic cells, Endothelial cells, Mesenchymal Stem Cells
Biology Area
Cell Adhesion, Cell Biology, Immunology, Neuroinflammation, Neuroscience, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kinashi T, et al. 1995. J. Leukoc. Biol. 57:168.
3. Bevilacquea MP. 1993. Annu. Rev. Immunol. 11:767.
4. Koni PA, et al. 2001. J. Exp. Med. 193:741.

Gene ID
22329 View all products for this Gene ID
View information about CD106 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.

Other Formats

View All CD106 Reagents Request Custom Conjugation
Description Clone Applications
Biotin anti-mouse CD106 429 (MVCAM.A) FC
FITC anti-mouse CD106 429 (MVCAM.A) FC
LEAF™ Purified anti-mouse CD106 429 (MVCAM.A) FC, IHC-F, IP
Purified anti-mouse CD106 429 (MVCAM.A) FC,IHC-F,IP
Alexa Fluor® 488 anti-mouse CD106 429 (MVCAM.A) FC,IHC-F,SB
Alexa Fluor® 647 anti-mouse CD106 429 (MVCAM.A) FC,IHC-F,3D IHC
PE anti-mouse CD106 429 (MVCAM.A) FC
PerCP/Cyanine5.5 anti-mouse CD106 429 (MVCAM.A) FC
APC anti-mouse CD106 429 (MVCAM.A) FC
PE/Cyanine7 anti-mouse CD106 429 (MVCAM.A) FC
Pacific Blue™ anti-mouse CD106 429 (MVCAM.A) FC
Alexa Fluor® 594 anti-mouse CD106 429 (MVCAM.A) IHC-F
TotalSeq™-A0226 anti-mouse CD106 429 (MVCAM.A) PG
Ultra-LEAF™ Purified anti-mouse CD106 429 (MVCAM.A) FC,IHC-F,IP
TotalSeq™-C0226 anti-mouse CD106 429 (MVCAM.A) PG
TotalSeq™-B0226 anti-mouse CD106 429 (MVCAM.A) PG
Go To Top Version: 1    Revision Date: 11/30/2012

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Biotin anti-mouse CD106

  • FITC anti-mouse CD106

  • LEAF™ Purified anti-mouse CD106

  • Purified anti-mouse CD106

  • Alexa Fluor® 488 anti-mouse CD106

  • Alexa Fluor® 647 anti-mouse CD106

  • PE anti-mouse CD106

  • PerCP/Cyanine5.5 anti-mouse CD106

  • APC anti-mouse CD106

  • PE/Cyanine7 anti-mouse CD106

  • Pacific Blue™ anti-mouse CD106

  • Alexa Fluor® 594 anti-mouse CD106

  • TotalSeq™-A0226 anti-mouse CD106

  • Ultra-LEAF™ Purified anti-mouse CD106

  • TotalSeq™-C0226 anti-mouse CD106

  • TotalSeq™-B0226 anti-mouse CD106


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