Loading...

Brilliant Violet 711™ anti-human KLRG1 (MAFA) Antibody

Pricing & Availability
Clone
SA231A2 (See other available formats)
Regulatory Status
RUO
Other Names
CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1
Isotype
Mouse IgG2a, κ
Ave. Rating
Submit a Review
Product Citations
publications
/SA231A2_-Brilliant-Violet-711_-KLRG1_Antibody_031023
Human peripheral blood lymphocytes were stained with anti-human CD56 APC and anti-human KLRG1 (MAFA) (clone SA231A2) Brilliant Violet 711™ (left) or mouse IgG2a, κ Brilliant Violet 711™ isotype control (right).
  • /SA231A2_-Brilliant-Violet-711_-KLRG1_Antibody_031023
    Human peripheral blood lymphocytes were stained with anti-human CD56 APC and anti-human KLRG1 (MAFA) (clone SA231A2) Brilliant Violet 711™ (left) or mouse IgG2a, κ Brilliant Violet 711™ isotype control (right).
Compare all formats See Brilliant Violet 711™ spectral data
Cat # Size Price Quantity Check Availability Save
367743 25 tests 177€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
367744 100 tests 348€
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human KLRG1-transfected cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 711™ under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Brilliant Violet 711™ excites at 405 nm and emits at 711 nm. The bandpass filter 710/50 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 711™ is a trademark of Sirigen Group Ltd.


Learn more about Brilliant Violet™.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser
Violet Laser (405 nm)
RRID
AB_2936760 (BioLegend Cat. No. 367743)
AB_2936760 (BioLegend Cat. No. 367744)

Antigen Details

Structure
Type II membrane glycoprotein, one C-type lectin domain, one ITIM, 30 kD.
Distribution

Subsets of NK, effector and memory T cells.

Function
Inhibits cell activation and proliferation, marker of T cell senescence.
Interaction
AKT
Ligand/Receptor
E-, N-, and R- cadherins
Cell Type
NK cells, T cells
Biology Area
Immunology, Innate Immunity
Antigen References

1. Shi L, et al. 2014. J. Immunol. 192:649.

Gene ID
10219 View all products for this Gene ID
UniProt
View information about KLRG1 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 03/10/2023

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human KLRG1 (MAFA)

  • Alexa Fluor® 647 anti-human KLRG1 (MAFA)

  • Brilliant Violet 421™ anti-human KLRG1 (MAFA)

  • PerCP/Cyanine5.5 anti-human KLRG1 (MAFA)

  • PE/Dazzle™ 594 anti-human KLRG1 (MAFA)

  • APC anti-human KLRG1 (MAFA)

  • PE anti-human KLRG1 (MAFA)

  • FITC anti-human KLRG1 (MAFA)

  • APC/Fire™ 750 anti-human KLRG1 (MAFA)

  • PE/Cyanine7 anti-human KLRG1 (MAFA)

  • TotalSeq™-A0153 anti-human KLRG1 (MAFA)

  • APC/Cyanine7 anti-human KLRG1 (MAFA)

  • KIRAVIA Blue 520™ anti-human KLRG1 (MAFA) Antibody

  • TotalSeq™-B0153 anti-human KLRG1 (MAFA) Antibody

  • Alexa Fluor® 700 anti-human KLRG1 (MAFA)

  • APC/Fire™ 810 anti-human KLRG1 (MAFA) Antibody

  • TotalSeq™-D0153 anti-human KLRG1 (MAFA)

  • PE/Fire™ 810 anti-human KLRG1 (MAFA) Antibody

  • TotalSeq™-C0153 anti-human KLRG1 (MAFA)

  • Spark NIR™ 685 anti-human KLRG1 (MAFA)

  • PE/Fire™ 640 anti-human KLRG1 (MAFA)

  • Brilliant Violet 711™ anti-human KLRG1 (MAFA)
ProductsHere
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account