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Alexa Fluor® 488 anti-mouse CD36 Antibody

Pricing & Availability
Clone
HM36 (See other available formats)
Regulatory Status
RUO
Other Names
FAT, gpIIIb, gpIV
Isotype
Armenian Hamster IgG
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Product Citations
publications
HM36_Alx488_080607
Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with HM36 Alexa Fluor® 488
  • HM36_Alx488_080607
    Thioglycolate-elicited BALB/c mouse peritoneal macrophages stained with HM36 Alexa Fluor® 488
Compare all formats See Alexa Fluor® 488 spectral data
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102607 25 µg 81€
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102608 100 µg 184€
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Description

CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Full length version of the protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.


Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Hamilton R F, 2006. J. Biol. Chem. 281:34218.
  2. Stuart L M, 2007. J. Biol. Chem. doi:10.1074/jbc.M702887200.
  3. Hu Q, 2018. Nat Biomed Eng. 2(11): 831.
Product Citations
  1. Amano C, et al. 2015. PLoS One. 10: 0137207. PubMed
  2. Stuart L, et al. 2007. J Biol Chem. 282:27392. PubMed
  3. Koh HS, et al. 2021. Int J Mol Sci. 22:. PubMed
  4. Hamilton R, et al. 2006. J Biol Chem. 281:34218. PubMed
  5. Han S, et al. 2017. J Immunol. 10.4049/jimmunol.1700099. PubMed
  6. Feuerstein R, et al. 2015. J Immunol. 194:2735. PubMed
  7. Kaiser S, et al. 2020. Glia. 68:2427. PubMed
  8. Xu J, et al. 2020. PLoS Biol. 18:e3000837. PubMed
  9. Szilagyi K, et al. 2014. Cardiovasc Res. 104:467. PubMed
RRID
AB_528791 (BioLegend Cat. No. 102607)
AB_528792 (BioLegend Cat. No. 102608)

Antigen Details

Structure
Scavenger receptor superfamily, 85 kD
Distribution

Platelets, monocytes, macrophages, microvascular and mammary endothelial cells

Function
Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Ligand/Receptor
Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Cell Type
Endothelial cells, Macrophages, Monocytes, Platelets
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.

Gene ID
12491 View all products for this Gene ID
UniProt
View information about CD36 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 06/27/2014

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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