Purified anti-rat CD5 Antibody

Pricing & Availability
Clone
OX-19 (See other available formats)
Regulatory Status
RUO
Other Names
Ly-1, Tp67, Leu-1, T1, Lyt-1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
OX-19_Pure_061708.jpg
LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE
  • OX-19_Pure_061708.jpg
    LOU rat splenocytes stained with OX-19 purified, followed by anti-mouse IgG PE
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203501 100 µg 124 CHF
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Description

CD5 is a 67 kD glycoprotein, also known as Lyt-1, Ly-1 or Ly-12. It is a member of the scavenger receptor superfamily and primarily expressed on thymocytes and mature peripheral T lymphocytes, but not on NK cells, intestinal intraepithelial gamma/delta T cells. A CD5+ B cell subset (B-1) has not been characterized in that rat.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Rat thymocyte lentil lectin-binding glycoproteins
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
ICC - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Dallman MJ, et al. 1984. Eur. J. Immunol. 14:260.
  2. Vemeer LA, et al. 1994. Eur. J. Immunol. 24:585.
RRID
AB_1089042 (BioLegend Cat. No. 203501)

Antigen Details

Structure
CD5 is a 67 kD glycoprotein of scavenger receptor superfamily. It is expressed on thymocytes, T cells and small subset of B cells.
Distribution

Expressed on thymocytes, peripheral T cells, and some thymic dendritic cells. It should be noted that a CD5+ subset of B cells has not been characterized in the rat by OX-19. Most gamma/delta T cells do not express CD5.

Function
Important in T-B cell interaction.
Ligand/Receptor
CD72
Biology Area
Immunology, Costimulatory Molecules
Molecular Family
CD Molecules, TCRs
Antigen References

1. Vermeer LA, et al. 1994. Eur. J. Immunol. 24:585.

Gene ID
54236 View all products for this Gene ID
UniProt
View information about CD5 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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