Purified anti-rat CD44H (Pgp-1, H-CAM) Antibody

Pricing & Availability
OX-49 (See other available formats)
Regulatory Status
Other Names
Pgp-1, H-CAM, CD44s
Mouse IgG2a, κ
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Product Citations
LOU rat splenocytes stained with purified OX-49 conjugated to FITC
  • OX-49_FITC_061909.jpg
    LOU rat splenocytes stained with purified OX-49 conjugated to FITC
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203901 25 µg 65 CHF
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CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Rat T blasts from mixed lymphocyte reactions
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IHC, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Paterson DJ, et al. 1987. Mol Immunol. 24(12):1281
Product Citations
  1. Yamada S, et al. 2021. J Tissue Eng. 12:20417314211019375. PubMed
AB_1659203 (BioLegend Cat. No. 203901)

Antigen Details

A 80-95 kD cell surface glycoprotein
Expressed on most leukocytes. It is up-regulated when T cells and B cells are activated.
Involve in leukocyte adhesion and homing to lymphoid organs.
Cell Type
Leukocytes, T cells, B cells
Biology Area
Molecular Family
CD Molecules
Antigen References

1. Arch R, et al. 1992. Science 257 (5070):682
2. Mitnacht R, et al. 1995. Eur. J. Immunol. 25(2):328
3. Zheng Z, et al. 1995. J Cell Bio. 130(2):485
4. Westermann J, et al. 1994. Eur. J. Immunol. 24(10):2312

Gene ID
12505 View all products for this Gene ID
View information about CD44H on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 11.30.2012

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • Purified anti-rat CD44H (Pgp-1, H-CAM)

  • FITC anti-rat CD44H (Pgp-1, H-CAM)


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