Purified anti-mouse CD125 (IL-5Rα) Antibody

Pricing & Availability
DIH37 (See other available formats)
Regulatory Status
Other Names
IL-5Rα, IL-5 Receptor α subunity
Rat IgG2a, κ
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Product Citations
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153402 500 µg 305,00 CHF
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CD125 is a 60KDa type I transmembrane protein.  It is the ligand-specific α subunit of the heterodimeric interleukin 5 (IL-5) receptor. The signal-transducing β subunit of this receptor does not bind to any cytokines and is shared by the receptors for IL-3 and CSF2/GM-CSF.  IL-5 is mainly produced by Th2 cells and elevated IL-5 levels are associated with allergic disorders.  CD125 has also been found to interact with syndecan binding protein (SDCBP or syntenin), leading to the activation of the transcription factor SOX4.  The mouse CD125 is expressed on eosinophils, basophils, and B cells.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Murine IL-5Ralpha-hFcgamma1 fusion protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

AB_2715827 (BioLegend Cat. No. 153402)

Antigen Details

60 kD type I transmembrane protein

Eosinophils, basophils and B cells

IL-5 receptor
Cell Type
B cells, Basophils, Eosinophils
Biology Area
Cell Biology, Cell Proliferation and Viability, Immunology
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References

1. Takaki S, et al. 1990. EMBO J. 9:4367
2. Takatsu K, et al. 2011. Proc. Jpn. Acad. Ser B. 87:463.
3. Hitoshi Y, et al. 1990. J. Immunol. 144:4218.

Gene ID
16192 View all products for this Gene ID
View information about CD125 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 0    Revision Date: 09.07.2017

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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