Purified anti-human IgG Fc Recombinant Antibody

Pricing & Availability
Clone
QA19A42 (See other available formats)
Regulatory Status
RUO
Other Names
Immunoglobulin G
Isotype
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
publications
QA19A42_PURE_IgG-Fc_Recombinant_Antibody_092420.png
Human DLL4 transfected CHO cells were incubated with recombinant human Notch 1-IgG Fc fusion protein, then stained with anti-human IgG Fc (clone QA19A42) recombinant purified (filled histogram) or mouse IgG1, κ purified isotype control (open histogram) followed by anti-mouse IgG PE secondary antibody.
  • QA19A42_PURE_IgG-Fc_Recombinant_Antibody_092420.png
    Human DLL4 transfected CHO cells were incubated with recombinant human Notch 1-IgG Fc fusion protein, then stained with anti-human IgG Fc (clone QA19A42) recombinant purified (filled histogram) or mouse IgG1, κ purified isotype control (open histogram) followed by anti-mouse IgG PE secondary antibody.
Cat # Size Price Quantity Check Availability Save
366902 100 µg 330,00 CHF
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

IgG Fc is a homodimer composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2876688 (BioLegend Cat. No. 366902)

Antigen Details

Structure
Homodimer formed by the constant region of the IgG heavy chain
Ligand/Receptor
CD16, CD32, CD64
Cell Type
B cells, Basophils, Dendritic cells, Macrophages, Mast cells, Neutrophils, NK cells, Platelets
Biology Area
Adaptive Immunity, Cell Biology, Immunology, Innate Immunity
Molecular Family
Fc Receptors
Antigen References
  1. Paul WE. 2003. Fundamental Immunology. Lippincott Williams & Wilkins. Philadelphia PA.
Gene ID
3500 View all products for this Gene ID
UniProt
View information about IgG Fc on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 09.24.2020

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Insert Note Here
Save Close Clear
Lab Timer
Tools
Login / Register
Remember me
Forgot your password? Reset password?
Create an Account