Purified anti-human CD48 Antibody

Pricing & Availability
BJ40 (See other available formats)
Regulatory Status
Other Names
Blast-1, SLAMF2, HuLy-m3
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with purified BJ40, followed by anti-mouse IgG FITC
  • BJ40_Pure_021009.jpg
    Human peripheral blood lymphocytes stained with purified BJ40, followed by anti-mouse IgG FITC
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336702 100 µg 106 CHF
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CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested
IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation.

Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. 1997. Leucocyte Typing VI:White Cell Differentiation Antigens. Garland Publishing Inc.
  2. Wang R, et al. 2012. J. Leukoc Biol. 91:299. PubMed
Product Citations
  1. Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
  2. Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
AB_1227561 (BioLegend Cat. No. 336702)

Antigen Details

CD2 family, contains 2 IgSF domains, GPI-membrane anchored, 40-47 kD

Widely expressed on hematopoietic cells except granulocytes, platelets, and erythrocytes. Increased on T and B cells after activation

Contributes to T cell antigen recognition
Cell Targets
Lck, Fyn interact with cytoplasmic domain
Cell Type
B cells
Biology Area
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Fisher RC and Thorley-Lawson DA. 1991. Mol. Cell. Biol. 11:1614.
  2. Korinek V, et al. 1991. Immunogenetics 33:108.
  3. Leukocyte Typing IV. Knapp W, et al. (Eds) Oxford University Press (1989)
  4. Leukocyte Typing V. Schlossman S, et al. (Eds) Oxford University Press (1995)
Gene ID
962 View all products for this Gene ID
View information about CD48 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 2    Revision Date: 08.18.2022

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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