PE anti-human CD80 Recombinant Antibody

Pricing & Availability
Clone
QA18A16 (See other available formats)
Regulatory Status
RUO
Other Names
B7-1, B7, BB1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA18A16_PE_CD80_Antibody_1_022221
Human B-cell Burkitt's lymphoma cell line Raji was stained with CD80 recombinant (clone QA18A16) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
  • QA18A16_PE_CD80_Antibody_1_022221
    Human B-cell Burkitt's lymphoma cell line Raji was stained with CD80 recombinant (clone QA18A16) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
See PE spectral data
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370611 25 tests 90,00 CHF
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370612 100 tests 200,00 CHF
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Description

CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2890803 (BioLegend Cat. No. 370611)
AB_2890803 (BioLegend Cat. No. 370612)

Antigen Details

Structure
Ig superfamily, single chain type I transmembrane glycoprotein, 60 kD
Function
T cell costimulation
Ligand/Receptor
CD28, CD152 (CTLA-4)
Antigen References
  1. Good-Jacobson KL, et al. 2012. J Immunol. 188:4217-25.
  2. Kleinpeter P, et al. 2019. J Virol. 93:e00207-19.
  3. Haile ST, et al. 2014. Cancer Immunol Res. 2:610-5.
Gene ID
941 View all products for this Gene ID
UniProt
View information about CD80 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 02.22.2021

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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