PE anti-human CD59 Antibody

Pricing & Availability
p282 (H19) (See other available formats)
Regulatory Status
V S006
Other Names
Protectin, H19, 1F-5Ag, HRF20, MACIF, MIRL, P-18
Mouse IgG2a, κ
Ave. Rating
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Product Citations
Human peripheral blood lymphocytes stained with p282 PE
  • p282_PE_070207
    Human peripheral blood lymphocytes stained with p282 PE
See PE spectral data View Moxi Flow Data
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304707 25 tests 100,00 CHF
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304708 100 tests 220,00 CHF
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CD59 is a 19-25 kD glycosylphosphatidylinositol (GPI)-anchored glycoprotein also known as protectin, MACIF, and H19. It is broadly expressed on hematopoietic and non-hematopoietic cells. CD59 inhibits the cytolytic activity of complement by binding to C9, inhibiting incorporation into C5b-8, and preventing the terminal steps in complement polymerization of the membrane attack complex. CD59 has also been reported to play a role in T cell activation.

Product Details
Technical Data Sheet (pdf)

Product Details

Human, Baboon, Chimpanzee, Cynomolgus, Rhesus
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Plum T, et al. 2020. Immunity. 52(2):404-416. PubMed
  2. Fischer K, et al. 2016. Sci Rep. 6:29081. PubMed
  3. Davies L, et al. 2016. Stem Cells Trans Med. 5: 1485 - 1495. PubMed
AB_2275871 (BioLegend Cat. No. 304707)
AB_2076125 (BioLegend Cat. No. 304708)

Antigen Details

Ly6 superfamily, single chain GPI-linked membrane protein, 19-25 kD

All cell types

Blocks complement-mediated lysis by inhibiting MAC formation
Complement components C8, C9
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience, Costimulatory Molecules
Molecular Family
CD Molecules
Antigen References

1. Davies A, et al. 1993. Immunol. Res. 12:258.
2. Lachmann P. 1991. Immunol. Today 12:312.
3. Liszewski M, et al. 1996. Adv. Immunol. 61:201.

Gene ID
966 View all products for this Gene ID
View information about CD59 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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