PE anti-human CD56 (Subset MSC Marker) Antibody

Pricing & Availability
Clone
39D5 (See other available formats)
Regulatory Status
RUO
Workshop
V NK57
Other Names
NCAM-1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
39D5_PE_CD56_Antibody_011322
Human retinoblastoma cell line WERI-RB-1 stained with anti-human CD56 (Subset MSC Marker) (clone 39D5) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
  • 39D5_PE_CD56_Antibody_011322
    Human retinoblastoma cell line WERI-RB-1 stained with anti-human CD56 (Subset MSC Marker) (clone 39D5) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
See PE spectral data
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355503 25 tests 134 CHF
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355504 100 tests 335 CHF
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Description

CD56 is a single transmemberane glycoprotein also known as NCAM (neural cell adhesion molecule). It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
KG1a cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone 39D5 recognizes the epitope of CD56 that is selectively expressed on a subset of mesenchymal stem cells (MSC) population which are CD271bright cells.  It does not efficiently recognize natural killer cells. 

Product Citations
  1. de Andrade LF, et al. 2019. JCI Insight. 4:e133103. PubMed
  2. Guo M, et al. 2021. Front Oncol. 11:632540. PubMed
  3. Motedayyen H, et al. 2017. BMC Res Notes. . 10.1186/s13104-017-2880-6. PubMed
RRID
AB_2561552 (BioLegend Cat. No. 355503)
AB_2561553 (BioLegend Cat. No. 355504)

Antigen Details

Distribution

Mesenchymal stem cells

Cell Type
Mesenchymal Stem Cells
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Battula VL, et al. 2009. Haematologica 94:173.

Gene ID
4684 View all products for this Gene ID
UniProt
View information about CD56 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PE anti-human CD56 (Subset MSC Marker)

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