PE anti-human CD328 (Siglec-7) Antibody

Pricing & Availability
6-434 (See other available formats)
Regulatory Status
VIII 80652
Other Names
Siglec7 (Sialic-binding Ig like lectin 7), p75, AIRM1
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes stained with 6-434 PE and HCD56 (CD56) APC
  • 6-434_PE_011909.jpg
    Human peripheral blood lymphocytes stained with 6-434 PE and HCD56 (CD56) APC
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339203 25 tests 153 CHF
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339204 100 tests 347 CHF
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Siglec-7, also known as p75/AIRM1, is a 75 kD type I transmembrane protein and a member of the family of sialic acid-binding immunoglobulin-like lectins (Siglecs). It is primarily found on NK cells and monocytes. The cytoplasmic domain of Siglec-7 contains immunoreceptor tyrosine-based inhibitory motif (ITIM). CD328 mediates sialic acid-dependent cell-cell binding and functions as an inhibitory receptor of NK cells. CD328 preferentially binds to sialylated glycans with α2,8 disialyl and α2,6 sialyl residues.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Product Citations
  1. Caduff N, et al. 2021. Cell Reports. 35(5):109056. PubMed
  2. Bradley T et al. 2018. Cell. 175(2):387-399 . PubMed
  3. Rosenstock P, et al. 2017. Immunol Res. 65:1017. PubMed
AB_1501164 (BioLegend Cat. No. 339203)
AB_1501160 (BioLegend Cat. No. 339204)

Antigen Details

Type I transmembrane protein, Siglec family member, 75 kD

NK cells, monocytes

Inhibitory receptor of NK cells
Sialylated glycans (with α2,8 disialyl and α2,6 sialyl residues)
Cell Type
Monocytes, NK cells
Biology Area
Molecular Family
CD Molecules, Siglec Molecules
Antigen References
  1. Avril T, et al. 2006. Infection and Immunity 74:4133
  2. Avril T, et al. 2004. J. Immunol. 173:6841
  3. Yamaji T, et al. 2005. Glycobiology 15:667
Gene ID
27036 View all products for this Gene ID
View information about CD328 on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11.30.2012

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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