- S18006K (See other available formats)
- Regulatory Status
- Other Names
- IL-7 receptor α chain, IL-7Rα
- Rat IgG2b, λ
- Ave. Rating
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- Product Citations
|Cat #||Size||Price||Quantity Check Availability||Save|
|158211||25 µg||112 CHF|
|158212||100 µg||235 CHF|
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.Product Details
- Verified Reactivity
- Antibody Type
- Host Species
- Mouse IL7R-transfectants
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography and conjugated with KIRAVIA Blue 520™ under optimal conditions.
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* KIRAVIA Blue 520™ has an excitation maximum of 495 nm, and a maximum emission of 520 nm.
KIRAVIA Blue™ 520 is a trademark of Sony. This product is subject to proprietary rights of Sony and is made and sold under license from Sony Corporation. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Sony and the Sony logo are registered trademarks of Sony Corporation.
- Excitation Laser
Blue Laser (488 nm)
AB_2922490 (BioLegend Cat. No. 158211)
AB_2922490 (BioLegend Cat. No. 158212)
- Type I transmembrane glycoprotein, associate with CD132, 60-90 kD
Immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, bone marrow stromal cells
- T cell and immature B cell proliferation and development
- Cell Type
- B cells, T cells, Thymocytes
- Biology Area
- Immunology, Signal Transduction
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
- Sudo T, et al. 1993. Proc Natl Acad Sci USA. 90:9125.
- Okuno Y, et al. 2002. Proc Natl Acad Sci USA. 99:6246.
- Pillai M, et al. 2004. Leuk Lymphoma. 45:2403.
- Gene ID
- 16197 View all products for this Gene ID
- View information about CD127 on UniProt.org
Related Pages & Pathways
Other FormatsView All CD127 Reagents Request Custom Conjugation
|Purified anti-mouse CD127 (IL-7Rα)||S18006K||FC|
|PE anti-mouse CD127 (IL-7Rα)||S18006K||FC|
|APC anti-mouse CD127 (IL-7Rα) Antibody||S18006K||FC|
|FITC anti-mouse CD127 (IL-7Rα)||S18006K||FC|
|KIRAVIA Blue 520™ anti-mouse CD127 (IL-7Rα)||S18006K||FC|
|PE/Cyanine7 anti-mouse CD127 (IL-7Rα)||S18006K||FC|
|PE/Fire™ 640 anti-mouse CD127 (IL-7Rα)||S18006K||FC|
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