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FITC F(ab')2 Goat anti-human IgG Fcγ Antibody

Pricing & Availability
Clone
Poly23980 (See other available formats)
Regulatory Status
RUO
Isotype
Goat Polyclonal Ig
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Product Citations
publications
See FITC spectral data
Cat # Size Price Quantity Check Availability Save
398006 100 µg 101 CHF
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Description

IgG Fc is a homodimer that is composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through binding to Fc receptors such as CD16, CD32, CD64, and the complement factor C1.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Polyclonal
Host Species
Goat
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration
1.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Product Citations
  1. Wu J, et al. 2022. Mol Pharmacol. 102:161. PubMed
RRID
AB_2820064 (BioLegend Cat. No. 398006)

Antigen Details

Structure
Homodimer formed by the constant region of the IgG heavy chain
Distribution

B cells

Ligand/Receptor
CD16, CD32, and CD64
Cell Type
B cells
Biology Area
Immunology
Antigen References
  1. Paul WE. 2003. Fundamental Immunology. Lippincott, Williams & Wilkins, Philadelphia.
Gene ID
NA
UniProt
View information about IgG Fcgamma on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 10.02.2019

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • PE F(ab')2 Goat anti-human IgG Fcγ

  • FITC F(ab')2 Goat anti-human IgG Fcγ

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