Biotin anti-mouse CD134 (OX-40) Antibody

Pricing & Availability
OX-86 (See other available formats)
Regulatory Status
Other Names
Rat IgG1, κ
Ave. Rating
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Product Citations
Con A-stimulated C57BL/6 mouse splenocytes stained with biotinylated OX-86, followed by Sav-PE
  • OX-86_Biotin_090507
    Con A-stimulated C57BL/6 mouse splenocytes stained with biotinylated OX-86, followed by Sav-PE
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119403 50 µg 83 CHF
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CD134 is a type I integral membrane protein also known as OX-40, ACT35, and tumor necrosis factor receptor superfamily member 4 (TNFRSF4). This receptor is expressed on activated CD4+ and CD8+ T cells and B cells. The OX-40 receptor binds to the OX-40 ligand (CD252) to provide a costimulatory signal that is independent of CD28. Blockade of OX40-OX40 ligand interactions has been shown to ameliorate experimental EAE and inflammatory bowel disease, which implies that these interactions are important in the pathogenesis of some autoimmune diseases.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant mouse OX-40-CD4 chimeric protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone OX-86 has been reported to act as an agonist and stimulate OX-40.

Application References

(PubMed link indicates BioLegend citation)
  1. Higgins LM, et al. 1999. J. Immunol. 162:486. (FC, IHC)
  2. Al-Shamkhani A, et al. 1996. Eur. J. Immunol. 26:1695. (Costim)
  3. del Rio ML, et al. 2011. Transpl. Int. 24:501. (FC) PubMed
Product Citations
  1. Arce Vargas F et al. 2018. Cancer cell. 33(4):649-663 . PubMed
AB_345419 (BioLegend Cat. No. 119403)

Antigen Details

TNF receptor superfamily, 50 kD

Activated CD4+ and CD8T cells, activated B cells.

Receptor for OX-40 ligand, provides co-stimulatory signal for lymphocyte proliferation independent of CD28; thought to play a role in the pathogenesis of some autoimmune diseases
OX-40 ligand
Cell Type
B cells, T cells, Tregs
Biology Area
Molecular Family
CD Molecules, Immune Checkpoint Receptors
Antigen References

1. Al-Shamkhani A, et al. 1996. Eur. J. Immunol. 26:1695.
2. Weinberg AD, et al. 1999. J. Immunol. 162:1818.
3. Akira H, et al. 1999. J. Immunol. 162:7058.
4. Pippig SD, et al. 1999. J. Immunol. 163:6520.
5. Higgins LM, et al. 1999. J. Immunol. 162:486.

Gene ID
22163 View all products for this Gene ID
View information about CD134 on

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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  • PE/Dazzle™ 594 anti-mouse CD134 (OX-40)

  • Brilliant Violet 711™ anti-mouse CD134 (OX-40)

  • Brilliant Violet 605™ anti-mouse CD134 (OX-40)

  • APC/Fire™ 750 anti-mouse CD134 (OX-40)

  • PerCP/Cyanine5.5 anti-mouse CD134 (OX-40)

  • TotalSeq™-A0195 anti-mouse CD134 (OX-40)

  • Ultra-LEAF™ Purified anti-mouse CD134 (OX-40)

  • TotalSeq™-C0195 anti-mouse CD134 (OX-40)


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