About the webinar

Cell-based treatments such as CAR-T cell therapy have potent anti-cancer effects. However, researchers developing these therapies have several hurdles to overcome, including therapy resistance, side effects, and reduced efficacy in solid tumors.

In this webinar brought to you by The Scientist, researchers discuss their efforts to uncover mechanistic challenges and molecular insights that improve cell therapy discovery and development.

Topics to be covered

• CAR-T cell therapy challenges in acute myeloid leukemia (AML), including the complexity of target antigen selection
• Novel CAR-T cell therapy approaches
• Ex vivo and in vivo CRISPR editing to reprogram T cells
• Using CRISPR to discover new gene circuits, add synthetic receptors and transcriptional programs, and manufacture next-generation CAR-T cells