Purified anti-rat RT1D Antibody

Pricing & Availability
Clone
OX-17 (See other available formats)
Regulatory Status
RUO
Other Names
Rat MHC class II
Isotype
Mouse IgG1, κ
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Product Citations
publications
OX-17_Pure_070808.jpg
LOU rat splenocytes stained with purified OX-17, followed by anti-mouse IgG PE
  • OX-17_Pure_070808.jpg
    LOU rat splenocytes stained with purified OX-17, followed by anti-mouse IgG PE
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205401 100 µg $124
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Description

The OX-17 antibody reacts with a non-polymorphic determinant of rat MHC class II antigen.It is found primarily on the surface of B lymphocytes,macrophages,dendritic cells and other antigen presenting cells.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Wistar rat splenocyte membrane extract
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Mayrhofer G et al. 1983. Eur J Immunol 13:1122. Fukumoto T et al. 1982. Eur J Immunol 12:237
Product Citations
  1. Gillette R, et al. 2021. Toxicol Sci. 182:288. PubMed
  2. Harms AS, et al. 2017. Acta Neuropathol Commun. 0.267361111. PubMed
RRID
AB_1134230 (BioLegend Cat. No. 205401)

Antigen Details

Structure
The rat MHC class II RT1D is equivalent to mouse I-E antigen. It consists of two chain structure around 28-32 kd, non-covalently linked each other.
Distribution
The rat MHC class II antigen is expressed on antigen presenting cells, including B cells, macrophages and dendritic cells.
Function
Present antigenic peptide to engage TCR
Ligand/Receptor
Presenting antigenic peptide to TCR
Cell Type
Antigen-presenting cells, B cells, Macrophages, Dendritic cells
Biology Area
Immunology
Molecular Family
MHC Antigens
Antigen References

1. Mayrhofer G et al. 1983. Eur J Immunol 13:1122. Fukumoto T et al. 1982. Eur J Immunol 12:237

Gene ID
294270 View all products for this Gene ID
UniProt
View information about RT1D on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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