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Purified anti-rat CD98 Antibody

Pricing & Availability
Clone
6G2/CD98 (See other available formats)
Regulatory Status
RUO
Other Names
4F2, Ly10
Isotype
Mouse IgG2a, κ
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Product Citations
publications
6G2-CD98_PURE_CD98_Antibody_072920
Rat splenocytes were stained with purified anti-rat CD98 (clone 6G2/CD98) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by goat anti-mouse IgG PE.
  • 6G2-CD98_PURE_CD98_Antibody_072920
    Rat splenocytes were stained with purified anti-rat CD98 (clone 6G2/CD98) (filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by goat anti-mouse IgG PE.
  • 6G2slashCD98_PURE_CD98_Antibody_IHC-F_061421.png
    Frozen rat spleen section was fixed with 4% paraformaldehyde (PFA) for 10 minutes, and blocked with 5% FBS for 30 minutes at room temperature. Then the section was stained with 10 µg/ml of purified anti-rat CD98 (clone 6G2/CD98) overnight at 4°C, followed by 2.5 µg/mL of Alexa Fluor® 647 anti-mouse IgG (clone Poly4053) (red) for two hours at room temperature. Nuclei were counterstained with DAPI (blue). The image was captured by 10X objective.
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206402 100 µg $288
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Description

CD98 is a cell surface glycoprotein of 125 KDa consisting of an 85 KDa heavy chain and a 40 KDa light chain.It is expressed on T, B, NK cells, granulocytes and many cell lines and tumor cells.CD98 has been shown to be involved in sodium-dependent calcium flux in muscles cells and lymphocyte activation.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. For immunohistochemistry, a concentration range of 5.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2876579 (BioLegend Cat. No. 206402)

Antigen Details

Structure
Disulfide-linked heterodimer, 80 kD and 45 kD reduced, 125 kD unreduced
Distribution

Broadly expressed on activated and transformed cells, not hematopoietic cell-specific. Lower levels on resting cells

Function
Potential amino acid transporter (neutral and dibasic amino acids) also involved in the activation of lymphocytes and integrin signaling. May be a target antigen for NK cells
Cell Type
B cells, Granulocytes, Leukocytes, Lymphocytes, NK cells, T cells
Biology Area
Cell Adhesion, Cell Proliferation and Viability
Molecular Family
CD Molecules
Gene ID
50567 View all products for this Gene ID
UniProt
View information about CD98 on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 06/14/2021

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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