Purified anti-rat CD335 (NKp46) Antibody

Pricing & Availability
Clone
WEN23 (See other available formats)
Regulatory Status
RUO
Other Names
NCR1, NKP46, LY94
Isotype
Mouse IgG1, κ
Ave. Rating
Submit a Review
Product Citations
publications
WEN23_PURE_CD335_Antibody_031318
Rat splenocytes were stained with purified anti-rat CD335 (clone WEN23; left) or purified Mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG. The cells were then stained with APC anti-rat CD161.
  • WEN23_PURE_CD335_Antibody_031318
    Rat splenocytes were stained with purified anti-rat CD335 (clone WEN23; left) or purified Mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG. The cells were then stained with APC anti-rat CD161.
Cat # Size Price Quantity Check Availability Save
250802 100 µg $125.00
Check Availability


Need larger quantities of this item?
Request Bulk Quote
Description

CD335, also known as NKp46, is a glycoprotein of the natural cytotoxicity receptor (NCR) family with 2 Ig-like domains and a short cytoplasmic tail. CD335 expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. NKp46 functions as a cytotoxicity triggering receptor.

Product Details
Technical data sheet

Product Details

Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Rat NKp46 ectodomain recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2728231 (BioLegend Cat. No. 250802)

Antigen Details

Structure
Single-pass type I membrane protein, 46 kD; belongs to the natural cytotoxicity receptor (NCR) family; contains 2 Ig-like (immunoglobulin-like) domains.
Distribution

Mature and immature NK cells, subset of NKT cells, but not on CD1d-restricted NKT cells.

Function
NK cells activation
Ligand/Receptor
Viral hemagglutinins, heparan sulfate proteoglycans
Cell Type
NK cells, NKT cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References
  1. Westgaard IH, et al. 2004. J. Leuko. Biol. 76:1200.
  2. Falco M, et al. 1999. Immunol. Lett. 68:411.
  3. Caligiuri MA. 2008. Blood. 112:461.
Gene ID
117547 View all products for this Gene ID
UniProt
View information about CD335 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 0    Revision Date: 03/14/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

ProductsHere
Insert Note Here
Save Close Clear
Lab Timer
Tools
Login/Register
Remember me
Forgot your password? Reset Password
Request an Account