Purified anti-mouse CD256 (APRIL) Antibody

Pricing & Availability
A3D8 (See other available formats)
Regulatory Status
Other Names
Armenian Hamster IgG
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136702 500 µg $295.00
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CD256 (APRIL, TNFSF13, TALL2, TRDL1) a transmembranal protein of 26 kD, forms a homotrimeric molecule that is cleaved from the cell surface resulting in the soluble form of APRIL; it also forms heterotrimers with BLyS. Its receptor are TNFRSF13b/TACI and TNFRSF17/BCMA. Expressed by T cells, B cells, dendritic cells, monocytes, and macrophages, APRIL induces proliferation of T and B cells, promotes IgA class switching, downregulates T-cell dependent antibody responses, and regulates the growth of a variety of tumor cells.

Product Details
Technical data sheet

Product Details

Mouse, Human
Antibody Type
Host Species
Armenian Hamster
Fusion protein of murine Maltose binding protein (MBP) and soluble April
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.

ICFC - Quality tested
ELISA - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

AB_2240829 (BioLegend Cat. No. 136702)

Antigen Details

Transmembranal protein of 26 kD, forms a homotrimer that is cleaved from the cell surface resulting in the soluble form. forms heterotrimers with BLyS

T cells, B cells, dendritic cells, monocytes, and macrophages

Induces proliferation of T and B cells, promotes IgA class switching and downregulates T-cell dependent antibody responses, regulates the growth of a variety of tumor cells.
Proliferation, apoptosis inhibition, IgA class switch.
Cell Type
B cells, Dendritic cells, Macrophages, Monocytes, T cells
Biology Area
Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Signal Transduction
Molecular Family
Antigen References

1. Belnoue E, et al. 2008 Blood 111:2755.
2. Xie P, et al. 2007. Immunity 27:253.
3. Mohr E, et al. 2009. J. Immunol. 182:2113.
4. Tezuka H, et al. 2007. Nature 448:92.
5. Benson MJ, et al. 2008. J. Immunol. 180:3655.

Gene ID
69583 View all products for this Gene ID
View information about CD256 on UniProt.org

Related FAQs

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Go To Top Version: 6    Revision Date: 12/13/2021

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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  • Purified anti-mouse CD256 (APRIL)

  • PE anti-mouse CD256 (APRIL)

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