- W19035D (See other available formats)
- Other Names
- SLAMF6, LY108, TCOM, SF2000, NTBA
- Rat IgG2a, κ
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- Product Citations
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NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.Product Details
- Antibody Type
- Host Species
- Extracellular domain of hIL-21R
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- The antibody was purified by affinity chromatography.
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Type I transmembrane tyrosine-phosphorylated glycoprotein, CD2/CD150 subfamily, 60 kD
NK cells, T cells, B cells
- CD28 independent T cell costimulation, induction of NK cell cytotoxicity, regulation of B cell tolerance
- Antigen References
1. Yigit B, et al. 2019. Cancer Immunol. Res. 10.1158/2326-6066
2. Wu N, et al. 2016. Nature Immunol. 17, 387-396
3. Radomir L, et al. 2017. J. Immunol. 199(8) 2745-2757
- Gene ID
- 114836 View all products for this Gene ID
- View information about CD352 on UniProt.org
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