- L053E8 (See other available formats)
- Regulatory Status
- Other Names
- GPR 9-6, GPR28, CDw199, Chemokine Receptor 9
- Mouse IgG2a, κ
- Ave. Rating
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- Product Citations
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Human CD199, also known as CCR9, is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in the gut-associated immune response. It is highly expressed on different stages of thymocytes and upregulated on CD4+ CD8+ cells. Expression of CCR9 on γ/δ T cells in the intraepithelial and small intestine has been reported. The interaction of CCR9 with its ligand CCL25 (TECK, thymus-expressed chemokine) may direct the trafficking of developing T cells in the thymus and the generation of gut-specific immunological memory.Product Details
- Antibody Type
- Host Species
- Cells transfected with human CCR9
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
- Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2715934 (BioLegend Cat. No. 358917)
AB_2715935 (BioLegend Cat. No. 358918)
- A member of G-protein coupled receptors which contains seven transmembrane domains. Human CCR9 has above 80% amino acid sequence homology with its mouse counterpart.
CD4+CD8+ thymocytes, γ/δ T cells, subset of memory T cells
- May direct the trafficking of developing T cells in the thymus and generation of gut-specific immunological memory; co-receptor for HIV-1
- Cell Type
- T cells, Thymocytes
- Biology Area
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
1. Zaballos A, et al. 1999. J. Immunol. 162:5671.
2. Wurbel MA, et al. 2007. J. Immunol. 178:7598.
3. Wurbel MA, et al. 2006. Eur. J. Immunol. 36:73.
- Gene ID
- 10803 View all products for this Gene ID
- View information about CD199 on UniProt.org
- Does staining at room temperature or even at 37°C help for checking chemokine receptors expression?
Due to continuous recycling of many chemokine receptors, it may be worthwhile to consider staining at room temperature or at 37°C if the staining at lower temperature (which can potentially reduce receptor turnover) is not optimal.
|APC anti-human CD199 (CCR9)||L053E8||FC|
|PE/Cyanine7 anti-human CD199 (CCR9)||L053E8||FC|
|PE anti-human CD199 (CCR9)||L053E8||FC|
|Purified anti-human CD199 (CCR9)||L053E8||FC|
|PerCP/Cyanine5.5 anti-human CD199 (CCR9)||L053E8||FC|
|Alexa Fluor® 647 anti-human CD199 (CCR9)||L053E8||FC|
|Brilliant Violet 421™ anti-human CD199 (CCR9)||L053E8||FC|
|Biotin anti-human CD199 (CCR9)||L053E8||FC|
|PE/Dazzle™ 594 anti-human CD199 (CCR9)||L053E8||FC|
|TotalSeq™-A0843 anti-human CD199 (CCR9)||L053E8||PG|
|TotalSeq™-C0843 anti-human CD199 (CCR9)||L053E8||PG|
|TotalSeq™-B0843 anti-human CD199 (CCR9) Antibody||L053E8||PG|
|KIRAVIA Blue 520™ anti-human CD199 (CCR9)||L053E8||FC|
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Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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APC anti-human CD199 (CCR9)
PE/Cyanine7 anti-human CD199 (CCR9)
PE anti-human CD199 (CCR9)
Purified anti-human CD199 (CCR9)
PerCP/Cyanine5.5 anti-human CD199 (CCR9)
Alexa Fluor® 647 anti-human CD199 (CCR9)
Brilliant Violet 421™ anti-human CD199 (CCR9)
Biotin anti-human CD199 (CCR9)
PE/Dazzle™ 594 anti-human CD199 (CCR9)
TotalSeq™-A0843 anti-human CD199 (CCR9)
TotalSeq™-C0843 anti-human CD199 (CCR9)
TotalSeq™-B0843 anti-human CD199 (CCR9) Antibody
KIRAVIA Blue 520™ anti-human CD199 (CCR9)