PE/Cyanine7 anti-human TCR Vβ8 Antibody

Pricing & Availability
Clone
JR2 (JR.2) (See other available formats)
Regulatory Status
RUO
Other Names
Vbeta8
Isotype
Mouse IgG2b, κ
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Product Citations
publications
JR2JR2_PECy7_TCRVBeta8_Antibody_041818
Human peripheral blood lymphocytes were stained with Human TruStain FcX™ (Cat No. 422302) followed by True-Stain Monocyte Blocker™ (Cat No. 425103), CD3 (HIT3a) APC, andTCR Vß8 (JR2) PE/Cyanine7 (left) or mouse IgG2b, ? PE/Cyanine7 isotype control (right).
  • JR2JR2_PECy7_TCRVBeta8_Antibody_041818
    Human peripheral blood lymphocytes were stained with Human TruStain FcX™ (Cat No. 422302) followed by True-Stain Monocyte Blocker™ (Cat No. 425103), CD3 (HIT3a) APC, andTCR Vß8 (JR2) PE/Cyanine7 (left) or mouse IgG2b, ? PE/Cyanine7 isotype control (right).
See PE/Cyanine7 spectral data
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348107 25 tests $115.00
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348108 100 tests $265.00
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Description

Vβ8 T cell receptor (TCR Vβ8) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of T cells. In association with CD3 complex, TCR α/β functions recognition of antigen and initiating T cell mediated immune responses. Human Vβ8 has been described as the target of the streptococcal mitogenic exotoxin z (SMEZ) and SMEZ-2.

Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Lavoie PM, et al. 2005. Int. Immunol. 17:931
  2. Okas M, et al. 2010. J. Immunother. 33:96
RRID
AB_2728314 (BioLegend Cat. No. 348107)
AB_2728315 (BioLegend Cat. No. 348108)

Antigen Details

Structure
Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex
Distribution

Subset of T cells

Function
Antigen recognition
Ligand/Receptor
MHC-Peptide complex
Cell Type
T cells
Biology Area
Immunology, Adaptive Immunity
Molecular Family
TCRs
Antigen References

1. Proft T, et al. 1999. J. Exp. Med. 189:89.
2. Kelsen J, et al. 2004. Scand. J. Gastroenterol. 39:238.

Gene ID
6957 View all products for this Gene ID
UniProt
View information about TCR Vb8 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 04/19/2018

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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