PE anti-mouse IL-27Rα Antibody

Pricing & Availability
W16125D (See other available formats)
Regulatory Status
Other Names
interleukin27 receptor alpha, IL27ra, IL-27Ra, TCCR, WSX-1
Rat IgG2a, κ
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Product Citations
C57BL/6 splenocytes were stained with anti-mouse CD3ε Brilliant Violet 421™ and anti-mouse IL-27Rα (clone W16125D) PE (left) or rat IgG2a, κ PE isotype control (right).
  • W16125D_PE_IL-27Ralpha_Antibody_050421.png
    C57BL/6 splenocytes were stained with anti-mouse CD3ε Brilliant Violet 421™ and anti-mouse IL-27Rα (clone W16125D) PE (left) or rat IgG2a, κ PE isotype control (right).
See PE spectral data
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159003 25 µg $110.00
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69 kD glycosylated transmembrane subunit of IL-27 receptor complex consisting of IL27Ra (WSX-1, TCCR) and gp130 (CD130). Expressed on T cells, monocytes, and neutrophils and aside from its effect on innate immunity, is involved in dampening the extent of Th1 immune response post infection. Activity levels of  INF-γ and IL-17 producing T cells are regulated through this receptor which relays signal through Jak-STAT pathway.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Mouse IL-27Rα transfectant
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
AB_2892327 (BioLegend Cat. No. 159003)

Antigen Details


IL27Ra is expressed by T cells, monocytes, and neutrophils.

IL27Ra combines with gp130 to form a receptor complex whose activation by IL-27 leads to differing pathway-dependent effector activities.
Cell Type
Monocytes, Neutrophils, T cells
Biology Area
Molecular Family
Antigen References
  1. Takeda A, et al. 2003. J Immunol. 170:4886-90.
  2. Yoshida H & Hunter CA. 2015. Annu Rev Immunol. 33:417-43.
  3. Iwasaki Y, et al. 2015. Int J Mol Sci. 16:2851-63.
Gene ID
50931 View all products for this Gene ID
View information about IL-27Ralpha on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 05/04/2021

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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