PE anti-human IL-28RA Antibody

Pricing & Availability
Clone
MHLICR2a (See other available formats)
Regulatory Status
RUO
Other Names
IFNLR1, CRF-2-12, LICR2
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
MHLICR2a_PE_111708.jpg
Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
  • MHLICR2a_PE_111708.jpg
    Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
See PE spectral data
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337803 25 tests $120.00
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337804 100 tests $260.00
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Description The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity. Product Details
Technical data sheet

Product Details

Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Dumoutier L, et al.. 2004. J. Bio. Chem. 279:32269
Product Citations
  1. Ghosh S, et al. 2019. Commun Biol. 0.325. PubMed
RRID
AB_2125220 (BioLegend Cat. No. 337803)
AB_2125219 (BioLegend Cat. No. 337804)

Antigen Details

Structure
Single-pass type I membrane glycoprotein, one fibronectin III domain, Class II cytokine receptor, 57kD
Distribution
Broad tissue distribution at low level
Interaction
Coreceptor with IL-10RB
Ligand/Receptor
IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3)
Biology Area
Immunology
Molecular Family
Cytokine/Chemokine Receptors
Antigen References
1. Renauld et al. J. Nature reviews Imm. 2003 3:667.
2. Sheppard P et al. Nature Imm. 2003 4:63.
3. Zhou Z et al. J. Virol. 2007 81:7749.
Gene ID
163702 View all products for this Gene ID
UniProt
View information about IL-28RA on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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