PE anti-human CD159a (NKG2A) Antibody

Pricing & Availability
S19004C (See other available formats)
Regulatory Status
Other Names
Killer Cell Lectin Like Receptor C1, KLRC1, NK Cell Receptor A
Mouse IgG1, κ
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Product Citations
Human peripheral blood lymphocytes were stained with CD3 FITC and CD159a (NKG2A) (clone S19004C) PE (left) or mouse IgG1, κ PE isotype control (right).
  • S19004C_PE_CD159a_Antibody_050720
    Human peripheral blood lymphocytes were stained with CD3 FITC and CD159a (NKG2A) (clone S19004C) PE (left) or mouse IgG1, κ PE isotype control (right).
See PE spectral data
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375103 25 tests $125.00
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375104 100 tests $330.00
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CD159a, also known as NKG2A or KLRC1, is a type II transmembrane protein. It belongs to the killer cell lectin-like receptor family also known as the NKG2 family. It is expressed on NK and NKT cells and T cell subsets. NKG2A is an inhibitory NK cell receptor and it is expressed as a heterodimer with CD94. In human, NKG2A/CD94 complex interacts HLA-E on target cells and inhibits T cells and NK cell effector functions. Recent studies showed that NKG2A blockade enhances the anti-tumor effect of NK cell and CD8+ T cells.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Human NKG2A/CD94-transfectants
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA)
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

S19004C does not cross-react with mouse CD159a.

Product Citations
AB_2888861 (BioLegend Cat. No. 375103)
AB_2888861 (BioLegend Cat. No. 375104)

Antigen Details

Type II transmembrane proteins of the C-type lectin superfamily

NK cells, NKT cells, T cell subsets

Inhibiting NK cell receptor
Cell Type
Lymphocytes, NK cells, NKT cells, T cells
Biology Area
Immuno-Oncology, Immunology
Molecular Family
Immune Checkpoint Receptors
Antigen References
  1. Brooks AG, et al. 1999. J Immunol. 162:305-13.
  2. Kaiser BK, et al. 2008. Proc Natl Acad Sci U S A. 105: 6696-701.
  3. Braud VM, et al. 2003. Trends Immunol. 24:162-4.
  4. Kamiya T, et al. 2019. J Clin Invest. 129:2094.
  5. André P, et al. 2018. Cell. 175:1731.
Gene ID
3821 View all products for this Gene ID
Specificity (DOES NOT SHOW ON TDS):
Specificity Alt (DOES NOT SHOW ON TDS):
View information about CD159a on

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 05/07/2020

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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