PE anti-human CD102 (ICAM-2) Antibody

Pricing & Availability
Clone
CBR-IC2/2 (See other available formats)
Regulatory Status
RUO
Workshop
V BP363
Other Names
Intercellular Adhesion Molecule-2, ICAM-2
Isotype
Mouse IgG2a, κ
Ave. Rating
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Product Citations
publications
CBR-IC2slash2_PE_090808.jpg
Human peripheral blood lymphocytes stained with CBR-IC2/2 PE
  • CBR-IC2slash2_PE_090808.jpg
    Human peripheral blood lymphocytes stained with CBR-IC2/2 PE
See PE spectral data
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328505 25 tests $105.00
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328506 100 tests $240.00
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Description

CD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN and MAC-1.

Product Details
Technical data sheet

Product Details

Reactivity
Human, African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
ICAM-2 cDNA transfected COS cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications: immunoprecipitation(1), blocking the interaction between ICAM-2 and LFA-1(1), immunohistochemical staining(2) of frozen tissue sections

Application References

(PubMed link indicates BioLegend citation)
  1. DeFougerolles AR,et al.1991.J. Exp.Med.174:253.
  2. Van Herpen CML,et al.2005.Clin. Cancer Res.11:1899
Product Citations
  1. Agostinis C, et al. 2019. Int J Mol Sci. 1.947222222. PubMed
  2. Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed
RRID
AB_2295682 (BioLegend Cat. No. 328505)
AB_2122200 (BioLegend Cat. No. 328506)

Antigen Details

Structure
55 kD type I transmembrane glycoprotein, Ig superfamily
Distribution
Vascular endothelial cells, lymphocytes, monocytes, platelets
Function
Adhesion, costimulation
Ligand/Receptor
LFA-1, DC-SIGN, MAC-1
Cell Type
Endothelial cells, Lymphocytes, Monocytes, Platelets
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
1.Weber KSC, et al.2004.Inflammation.28:177.
2.Barclay A, et al.1997 The Leukoycte Antigen FactsbookAcademic Press.
3. Casasnovas JM, et al.1999.P. Natl. Acad. Sci. USA96:3017.
4. Diamonds MS, et al.1990. J. Cell Biol.111:3129.
Gene ID
3384 View all products for this Gene ID
UniProt
View information about CD102 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.

 

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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