- WEN23 (See other available formats)
- Regulatory Status
- Other Names
- NCR1, NKP46, LY94
- Mouse IgG1, κ
- Ave. Rating
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- Product Citations
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CD335, also known as NKp46, is a glycoprotein of the natural cytotoxicity receptor (NCR) family with 2 Ig-like domains and a short cytoplasmic tail. CD335 expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. NKp46 functions as a cytotoxicity triggering receptor.Product Details
- Antibody Type
- Host Species
- Rat NKp46 ectodomain recombinant protein
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
AB_2728234 (BioLegend Cat. No. 250805)
AB_2728235 (BioLegend Cat. No. 250806)
- Single-pass type I membrane protein, 46 kD; belongs to the natural cytotoxicity receptor (NCR) family; contains 2 Ig-like (immunoglobulin-like) domains.
Mature and immature NK cells, subset of NKT cells, but not on CD1d-restricted NKT cells.
- NK cells activation
- Viral hemagglutinins, heparan sulfate proteoglycans
- Cell Type
- NK cells, NKT cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
- Westgaard IH, et al. 2004. J. Leuko. Biol. 76:1200.
- Falco M, et al. 1999. Immunol. Lett. 68:411.
- Caligiuri MA. 2008. Blood. 112:461.
- Gene ID
- 117547 View all products for this Gene ID
- View information about CD335 on UniProt.org
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