- MB19-1 (See other available formats)
- Regulatory Status
- Other Names
- Mouse IgA, κ
- Ave. Rating
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- Product Citations
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CD19 is a 95 kD glycoprotein, also known as B4. It is a member of the Ig superfamily, expressed on all pro-B to mature B cells (during development) and follicular dendritic cells. Plasma cells do not express CD19. CD19, in association with CD21 and CD81 forms a molecular complex integral to B cell activation.Product Details
- Antibody Type
- Host Species
- mouse CD19+ pre-B cell line 300.19
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunoprecipitation3, and in vitro costimulation (synergistic with anti-IgM) of B cell activation1,2.
(PubMed link indicates BioLegend citation)
- Sato S, et al. 1997. J. Immunol. 158:4662. (Costim)
- Sato S, et al. 1997. P. Natl. Acad. Sci. USA 94:13158. (Costim)
- Krop I, et al. 1996. Eur. J. Immunol. 26:238. (IP)
- Sato S, et al. 1996. J. Immunol. 157:4371.
- Stolk M, et al. 2006. J. Leukoc. Biol. doi:10.1189/jlb.1205739. (FC)
- Shime H, et al. 2012. PNAS. 109:2066. PubMed.
- Product Citations
AB_312824 (BioLegend Cat. No. 101505)
AB_312825 (BioLegend Cat. No. 101506)
- Ig superfamily, associates with CD21 and CD81, 95 kD
Pro-B cells to mature B cells (during development), follicular dendritic cells
- Modulates B cell activation and differentiation
- CD21, CD81, Leu-13
- Cell Type
- B cells, Dendritic cells
- Biology Area
- Immunology, Costimulatory Molecules
- Molecular Family
- CD Molecules
- Antigen References
1. Fearon DT. 1993. Curr. Opin. Immunol. 5:341.
2. Krop I, et al. 1996. Eur. J. Immunol. 26:238.
3. Krop I, et al. 1996. J. Immunol. 157:48.
4. Tedder TF,et al. 1994. Immunol. Today 15:437.
- Gene ID
- 12478 View all products for this Gene ID
- View information about CD19 on UniProt.org
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