FITC anti-human CLEC1B (CLEC2) Antibody

Pricing & Availability
AYP1 (See other available formats)
Regulatory Status
Other Names
C-type lectin domain family 1 member B, CLEC2B, PRO1384, QDED721
Mouse IgG1, κ
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Product Citations
Human platelets were stained with CLEC1B (clone AYP1) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
  • AYP1_FITC_CLEC1B_Antibody_021317
    Human platelets were stained with CLEC1B (clone AYP1) FITC (filled histogram) or mouse IgG1, κ FITC isotype control (open histogram).
See FITC spectral data
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372007 25 tests $100
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372008 100 tests $235
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C-type lectin domain family 1 member B (CLEC1B, CLEC2) is a 32kD, type II transmembrane protein, highly expressed on platelets and megakaryocytes. CLEC1B is involved in platelet activation and aggregation, and mediates the capture of HIV-1 by platelets. CLEC1B contains one hem-immunoreceptor tyrosine-based activation motif (hemITAM) though which interact with Syk and PLC-g. The known ligands of CLEC1B are rhodocytin and podoplanin.

Product Details
Technical data sheet

Product Details

Antibody Type
Host Species
Extracellular region of CLEC1B (amino acids 68-229).
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Lot-specific (please contact technical support for concentration and total µg amount, or use our Lookup tool if you have a lot number.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation; inhibition of podoplanin and rhodocytin-mediated platelet activation.

Application References

(PubMed link indicates BioLegend citation)
  1. Gitz E, et al. 2014. Blood 124:2262.
AB_2650868 (BioLegend Cat. No. 372007)
AB_2650869 (BioLegend Cat. No. 372008)

Antigen Details

Type II transmembrane protein, 32 kD, homodimer, 1 hemITAM motif.
Platelets, megakaryocytes; low expression on myeloid cells.
Mediates platelet activation and aggregation; facilitates capture of HIV by platelets.
Syk, PLC-g.
Rhodocytin, podoplanin.
Cell Type
Platelets, Megakaryocytes, Dendritic cells
Biology Area
Antigen References

1. Manne BK, et al. 2015. J. Biol. Chem. 290:11557.
2. Hughes CE, et al. 2013. J. Biol. Chem. 288:5127.
3. Parguiña AF, et al. 2012. Blood 120:e117-26.
4. Osada M, et al. 2012. J. Biol. Chem. 287:22241.

Gene ID
51266 View all products for this Gene ID
View information about CLEC1B on

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Go To Top Version: 1    Revision Date: 02/15/2017

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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